NP_033738.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,019 Da
NCBI Official Full Name
actin, alpha cardiac muscle 1
NCBI Official Synonym Full Names
actin, alpha, cardiac muscle 1
NCBI Official Synonym Symbols
NCBI Protein Information
actin, alpha cardiac muscle 1
UniProt Protein Name
Actin, alpha cardiac muscle 1
UniProt Synonym Protein Names
Alpha-cardiac actin
UniProt Synonym Gene Names
UniProt Entry Name
ACTC_MOUSE
UniProt Comments for ACTC1
ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Motility/polarity/chemotaxis; Contractile; Cytoskeletal; Cell development/differentiation; Myosin-binding
Cellular Component: I band; extracellular space; sarcomere; focal adhesion; cytoskeleton; membrane; cytoplasm; actin filament
Molecular Function: myosin binding; ATPase activity; nucleotide binding; ATP binding
Biological Process: actin filament-based movement; metabolic process; muscle thin filament assembly; heart contraction; actomyosin structure organization and biogenesis; cardiac muscle morphogensis; actin-myosin filament sliding; cardiac myofibril assembly; cardiac muscle contraction; negative regulation of apoptosis
Research Articles on ACTC1
Precautions
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Disclaimer
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Products associated with ACTC1 sirna
Pathways associated with ACTC1 sirna
Diseases associated with ACTC1 sirna
Disease Name |
Pubmed Publications |
Cardiovascular Diseases Antibodies |
>32 publications with ACTC1 and Cardiovascular Diseases |
Cardiomyopathy, Dilated Antibodies |
>9 publications with ACTC1 and Cardiomyopathy, Dilated |
Cardiomegaly Antibodies |
>6 publications with ACTC1 and Cardiomegaly |
Cardiomyopathy, Familial Hypertrophic, 1 Antibodies |
>5 publications with ACTC1 and Cardiomyopathy, Familial Hypertrophic, 1 |
Hypertrophy Antibodies |
>4 publications with ACTC1 and Hypertrophy |
Disease Models, Animal Antibodies |
>2 publications with ACTC1 and Disease Models, Animal |
Lung Neoplasms Antibodies |
>2 publications with ACTC1 and Lung Neoplasms |
Lung Diseases Antibodies |
>2 publications with ACTC1 and Lung Diseases |
Refractive Errors Antibodies |
>2 publications with ACTC1 and Refractive Errors |
Cardiomyopathy, Familial Hypertrophic, 11 Antibodies |
>2 publications with ACTC1 and Cardiomyopathy, Familial Hypertrophic, 11 |
Organs/Tissues associated with ACTC1 sirna
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