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anti-5-HT-1A antibody :: 5-HT-1A Antibody

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Catalog # MBS858295
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Western Blot (WB)
Product Name

5-HT-1A, Antibody

Also Known As

5-HT-1A Antibody

Product Synonym Names
5-HT1A; 5-hydroxytryptamine 1A receptor; 5HT1A; G-21; HTR1A; Serotonin receptor 1A
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
422
OMIM
109760
3D Structure
ModBase 3D Structure for P08908
Species Reactivity
Human, Mouse, Rat
Specificity
5-HT-1A antibody detects endogenous levels of total 5-HT-1A protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human 5-HT-1A.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-5-HT-1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-5-HT-1A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-5-HT-1A antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-5-HT-1A antibody
Western blot analysis of extracts from HepG2 cells and Jurkat cells, using 5-HT-1A antibody.
anti-5-HT-1A antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for 5-HT-1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,107 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 1A
NCBI Official Symbol
HTR1A  [Similar Products]
NCBI Official Synonym Symbols
G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
G-21; Serotonin receptor 1A
UniProt Gene Name
HTR1A  [Similar Products]
UniProt Synonym Gene Names
ADRB2RL1; ADRBRL1; 5-HT-1A; 5-HT1A  [Similar Products]
NCBI Summary for 5-HT-1A
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
UniProt Comments for 5-HT-1A
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Product References and Citations for anti-5-HT-1A antibody
Kobilka B.K., Nature 329:75-79(1987). The MGC Project Team, Genome Res. 14:2121-2127(2004). Parks C.L., Nucleic Acids Res. 19:7155-7160(1991).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Products associated withanti-5-HT-1A antibody
Organs/Tissues associated with anti-5-HT-1A antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >51 publications with 5-HT-1A and Brain
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