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anti-5HT7 R antibody :: 5-HT (Serotonin) 7 Antibody

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Catalog # MBS555179
Unit / Price
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  0.1 mL  /  $525 +1 FREE 8GB USB
Testing Data
Product Name

5-HT (Serotonin) 7 (5HT7 R), Antibody

Full Product Name

5-HT (Serotonin) 7 Receptor Antibody, Rabbit

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
182137
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified - Liquid
Type Info
Rabbit IgG
Immunogen
synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor
Preparation and Storage
Store at 4-8 degrees
Other Notes
Small volumes of anti-5HT7 R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-5HT7 R antibody
The histochemical antibody for 5-HT7 receptor is generated in a rabbit against synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor.

The antibody produces 4+ (maximum) labeling of 5-HT7 receptor at dilutions of 1/100 - 1/300 using biotin-avidin/HRP technique in rat cortex and hippocampus. Optimal dilution will vary depending upon fixation, labeling technique and/or detection system; therefore, a dilution series is recommended. The antibody was characterized by immunohistochemistry. Immunohistochemical staining of rat brain correlates well with Northern blot analysis, in situ hybridization and receptor autoradiography studies. Immunolabeling is completely abolished by preadsorption with synthetic rat 5-HT7 receptor (8-23). BlastP database sequence homology searches indicate that the amino acid sequence is unique to rat 5-HT7A, 5-HT7B and 5-HT7C. There is also significant sequence overlap with the mouse and human forms.
Applications Tested/Suitable for anti-5HT7 R antibody
Immunohistochemistry (IHC), Western Blot (WB)

Testing Data of anti-5HT7 R antibody
anti-5HT7 R antibody Testing Data image
NCBI/Uniprot data below describe general gene information for 5HT7 R. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,984 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 7 isoform b
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 7
NCBI Official Symbol
NCBI Official Synonym Symbols
5-HT7
  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 7
UniProt Protein Name
5-hydroxytryptamine receptor 7
UniProt Synonym Protein Names
5-HT-X; Serotonin receptor 7
UniProt Gene Name
UniProt Synonym Gene Names
5-HT-7; 5-HT7  [Similar Products]
UniProt Entry Name
5HT7R_HUMAN
UniProt Comments for 5HT7 R
5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 10q21-q24

Cellular Component: dendrite; integral to plasma membrane; plasma membrane

Molecular Function: neurotransmitter receptor activity

Biological Process: blood circulation; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor, adenylate cyclase activating pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-5HT7 R antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with 5HT7 R and Brain
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