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A-366 biochemical

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Catalog # MBS842453
Unit / Price
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  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $440 +1 FREE 8GB USB
Structure
Product Name

A-366, Biochemical

Full Product Name

A-366

Product Synonym Names
5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>=98% by HPLC
Form/Format
Appearance: Off-white solid
CAS Number
1527503-11-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO (>25 mg/ml)
SMILES
NC(C12CCC1)=NC3=C2C=C(OC)C(OCCCN4CCCC4)=C3
InChi
InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
InChi Key
BKCDJTRMYWSXMC-UHFFFAOYSA-N
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Other Notes
Small volumes of A-366 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
A-366 biochemical
Background: A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC?? = 3.3 nM). It displays >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. A-366 has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells with an IC?? of 100 nM.

Structure of A-366 biochemical
A-366 biochemical Structure image
Molecular Weight
329.44
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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