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A1CF cdna clone

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Catalog # MBS1269966
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
A1CF cdna clone
Product Name

A1CF, cDNA Clone

Full Product Name

A1CF cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
atggaatcaa atcacaaatc cggggatgga ttgagcggca ctcagaagga agcagccctc cgcgcactgg tccagcgcac aggatatagc ttggtccagg aaaatggaca aagaaaatat ggtggccctc cacctggttg ggatgctgca ccccctgaaa ggggctgtga aatttttatt ggaaaacttc cccgagacct ttttgaggat gagcttatac cattatgtga aaaaatcggt aaaatttatg aaatgagaat gatgatggat tttaatggca acaatagagg atatgcattt gtaacatttt caaataaagt ggaagccaag aatgcaatca agcaacttaa taattatgaa attaggtaa
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of A1CF cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for A1CF. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,871 Da
NCBI Official Full Name
Homo sapiens APOBEC1 complementation factor, mRNA
NCBI Official Synonym Full Names
APOBEC1 complementation factor
NCBI Official Symbol
NCBI Official Synonym Symbols
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NCBI Protein Information
APOBEC1 complementation factor
UniProt Protein Name
APOBEC1 complementation factor
UniProt Synonym Protein Names
APOBEC1-stimulating protein
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
NCBI Summary for A1CF
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
UniProt Comments for A1CF
ACF: Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; RNA-binding; RNA processing

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: apolipoprotein B mRNA editing enzyme complex; cytoplasm; nucleoplasm

Molecular Function: double-stranded RNA binding; protein binding; RNA binding; single-stranded RNA binding

Biological Process: cytidine to uridine editing; protein stabilization
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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