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A2LD1 recombinant protein :: AIG2-Like Domain 1 Recombinant Protein

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Catalog # MBS144470
Unit / Price
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  0.002 mg  /  $140 +1 FREE 8GB USB
  0.01 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $5,015 +6 FREE 8GB USB
A2LD1 recombinant protein
Product Name

AIG2-Like Domain 1 (A2LD1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human AIG2-Like Domain 1

Product Synonym Names
A2LD1 Human; AIG2-Like Domain 1 Human Recombinant; Gamma-glutamylaminecyclotransferase; GGACT; AIG2-like domain-containing protein 1; A2LD1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MALVFVYGTL KRGQPNHRVL RDGAHGSAAF RARGRTLEPY PLVIAGEHNI PWLLHLPGSG RLVEGEVYAV DERMLRFLDD FESCPALYQR TVLRVQLLED RAPGAEEPPA PTAVQCFVYS RATFPPEWAQ LPHHDSYDSE GPHGLRYNPR ENR
OMIM
613378
3D Structure
ModBase 3D Structure for Q9BVM4
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The A2LD1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Sterile Filtered colorless solution.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Other Notes
Small volumes of A2LD1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
A2LD1 recombinant protein
Introduction: Gamma-glutamylaminecyclotransferase (A2LD1) is an enzyme which converts gamma-glutamylamines to free amines and 5-oxoproline. A2LD1 demonstrates high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and other proteins cross-linked by transglutaminases. A2LD1 assists in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, which is a byproduct of fibrin degradation. The reaction catalyzed by the A2LD1 produces 5-oxo-L-proline and a free alkylamine.
NCBI/Uniprot data below describe general gene information for A2LD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,329 Da
NCBI Official Full Name
gamma-glutamylaminecyclotransferase
NCBI Official Synonym Full Names
gamma-glutamylamine cyclotransferase
NCBI Official Symbol
GGACT  [Similar Products]
NCBI Official Synonym Symbols
A2LD1
  [Similar Products]
NCBI Protein Information
gamma-glutamylaminecyclotransferase; AIG2-like domain 1; AIG2-like domain-containing protein 1
UniProt Protein Name
Gamma-glutamylaminecyclotransferase
UniProt Synonym Protein Names
AIG2-like domain-containing protein 1; Gamma-glutamylamine cyclotransferase
UniProt Gene Name
GGACT  [Similar Products]
UniProt Synonym Gene Names
A2LD1; GGACT  [Similar Products]
UniProt Entry Name
GGACT_HUMAN
NCBI Summary for A2LD1
The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]
UniProt Comments for A2LD1
A2LD1: Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. Belongs to the gamma-glutamylcyclotransferase family.

Protein type: Transferase; EC 2.3.2.4

Chromosomal Location of Human Ortholog: 13q32.3

Molecular Function: gamma-glutamylcyclotransferase activity

Biological Process: amino acid derivative catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with A2LD1 recombinant protein
 Reference Product  PubMed Publications
 GGCT recombinant protein  >1 publications with A2LD1 and GGCT
Organs/Tissues associated with A2LD1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with A2LD1 and Kidney
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