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A4GALT cdna clone

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Catalog # MBS1278132
Unit / Price DISCONTINUED
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A4GALT cdna clone
Product Name

A4GALT, cDNA Clone

Also Known As

A4GALT cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
2065
Sequence
Please Inquire
OMIM
111400
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of A4GALT cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for A4GALT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,499 Da
NCBI Official Full Name
Homo sapiens alpha 1,4-galactosyltransferase, mRNA
NCBI Official Synonym Full Names
alpha 1,4-galactosyltransferase
NCBI Official Symbol
A4GALT  [Similar Products]
NCBI Official Synonym Symbols
P1; PK; Gb3S; P(k); P1PK; A14GALT; A4GALT1
  [Similar Products]
NCBI Protein Information
lactosylceramide 4-alpha-galactosyltransferase
UniProt Protein Name
Lactosylceramide 4-alpha-galactosyltransferase
UniProt Synonym Protein Names
Alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
UniProt Gene Name
A4GALT  [Similar Products]
UniProt Synonym Gene Names
A14GALT; A4GALT1; Gb3 synthase  [Similar Products]
UniProt Entry Name
A4GAT_HUMAN
NCBI Summary for A4GALT
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
UniProt Comments for A4GALT
A4GALT: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. Belongs to the glycosyltransferase 32 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Transferase; Membrane protein, integral; EC 2.4.1.228

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: membrane

Molecular Function: galactosyltransferase activity

Biological Process: plasma membrane organization and biogenesis

Disease: Blood Group, P1pk System
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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