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A83-01 inhibitor

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Catalog # MBS515040
Unit / Price
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  5 mg  /  $210 +1 FREE 8GB USB
  25 mg  /  $535 +1 FREE 8GB USB
Molecular Structure
Product Name

A83-01, Inhibitor

Full Product Name


Product Synonym Names
AR-A014418 ; N-[(4-Methoxyphenyl) methyl]-N'-(5-nitro-2-thiazolyl)urea; 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
>98% (TLC); NMR (Conforms)
Light Yellow powder
CAS Number
Molecular Formula
GSK3b inhibitor
May be dissolved in DMSO (30mg/ml)
May be dissolved in DMSO (20mg/ml)
Preparation and Storage
Store desiccated as supplied at -20 degree C for up to 2 years. Store solutions at -20 degree C for up to 2 months.
Other Notes
Small volumes of A83-01 inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
A83-01 inhibitor
ALK inhibitor
Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50=104 nM). Inhibits -amyloid-mediated neurodegeneration in hippocampal slices. Antiinflammatory activity. Cell permeable. Active in rodent models.

Scientific Background: Potent and selective ALK4, 5 and 7 inhibitor (1,2). IC50=45, 12, 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFbeta (2). Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency (3). Together with AMI-5 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts (4). Active in rat models. Cell permeable

Molecular Structure of A83-01 inhibitor
A83-01 inhibitor Molecular Structure image
Molecular Weight
Product References and Citations for A83-01 inhibitor
R Bhat et al. J. Biol. Chem. 2003 278: 45937
SH Ramirez et al. Am. J. Pathol. 2010 176:881

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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