• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AADAC cdna clone

Scan QR to view Datasheet
Catalog # MBS1265705
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
AADAC cdna clone
Product Name

AADAC, cDNA Clone

Full Product Name

AADAC cDNA Clone

Product Gene Name

AADAC cdna clone

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
TOP
Sequence
atgggaagaa aatcgctgta ccttctgatt gtggggatcc tcatagcata ttatatttat acgcctctcc cagataacgt tgaggagcca tggagaatga tgtggataaa cgcacatctg aaaactatac aaaatttggc tacatttgtg gagctcctgg gacttcacca ttttatggat tcctttaagg ttgtcgggag ctttgatgaa gtcccaccaa cctcagatga aaatgtcact gtgactgaga caaaattcaa caacattctt gttcgggtat atgtgccaaa gagaaagtct gaagcactaa gaagggggtt gttttacatc catggtggag gctggtgcgt gggaagtgct gctctaagtg gttatgactt gctgtcaaga tggacagcag acagacttga tgctgtcgtc gtatcaacca actacagatt agcacctaag tatcatttcc caattcaatt tgaagatgta tataatgcct taaggtggtt cttacgtaaa aaagttcttg caaaatatgg tgtgaaccct gagagaatcg gtatttctgg agatagtgca ggagggaatt tagctgcagc agtgactcaa cagctccttg atgacccaga tgtcaagatc aaactcaaga tccagtcttt aatttatcct gcccttcagc ctcttgatgt agatttaccg tcatatcaag aaaattcaaa ttttctattt ctatccaaat cactcatggt cagattctgg agtgaatatt ttaccactga tagatcactt gaaaaagcca tgctttccag acaacatgta cctgtggaat caagtcatct cttcaaattt gttaattgga gttccctgct ccctgagagg tttataaaag gacatgttta taacaatcca aattatggca gttctgagct ggctaaaaaa tatccagggt tcctagatgt gagggcagcc cctttgttgg ctgatgacaa caaattacgt ggcttacccc tgacctatgt catcacctgt caatatgatc tcttaagaga tgatggactc atgtatgtca cccgacttcg caacactggg gttcaggtga ctcataacca tgttgaggat ggattccatg gagcattttc atttctggga cttaaaatta gtcacagact tataaatcag tatattgagt ggctaaagga aaatctatag
OMIM
600338
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of AADAC cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
TOP
NCBI/Uniprot data below describe general gene information for AADAC. It may not necessarily be applicable to this product.
NCBI GI #
21595550
NCBI GeneID
13
NCBI Accession #
BC032309 [Other Products]
UniProt Secondary Accession #
Q8N1A9; A8K3L3; D3DNJ6[Other Products]
UniProt Related Accession #
P22760[Other Products]
Molecular Weight
45,734 Da
TOP
NCBI Official Full Name
Homo sapiens arylacetamide deacetylase (esterase), mRNA
NCBI Official Synonym Full Names
arylacetamide deacetylase
NCBI Official Symbol
AADAC  [Similar Products]
NCBI Official Synonym Symbols
DAC; CES5A1
  [Similar Products]
NCBI Protein Information
arylacetamide deacetylase
UniProt Protein Name
Arylacetamide deacetylase
Protein Family
Arylacetamide deacetylase
UniProt Gene Name
AADAC  [Similar Products]
UniProt Synonym Gene Names
DAC  [Similar Products]
UniProt Entry Name
AAAD_HUMAN
TOP
NCBI Summary for AADAC
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]
TOP
UniProt Comments for AADAC
AADAC: Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores. Belongs to the 'GDXG' lipolytic enzyme family.

Protein type: Endoplasmic reticulum; Deacetylase; EC 3.1.1.3; Motility/polarity/chemotaxis; Membrane protein, integral; Lipase

Chromosomal Location of Human Ortholog: 3q25.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: catalytic activity; deacetylase activity; lipase activity; serine hydrolase activity; triacylglycerol lipase activity

Biological Process: xenobiotic metabolic process
Research Articles on AADAC
1. Translational N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.
TOP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
TOP
Diseases associated with AADAC cdna clone
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >2 publications with AADAC and Drug Toxicity
 Hepatitis Antibodies  >1 publications with AADAC and Hepatitis
 Carcinoma, Hepatocellular Antibodies  >1 publications with AADAC and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with AADAC and Liver Neoplasms
 Fatty Liver Antibodies  >1 publications with AADAC and Fatty Liver
 Liver Diseases Antibodies  >1 publications with AADAC and Liver Diseases
Organs/Tissues associated with AADAC cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >13 publications with AADAC and Liver
 Adipose Tissue Antibodies  >1 publications with AADAC and Adipose Tissue
 Connective Tissue Antibodies  >1 publications with AADAC and Connective Tissue
 Pancreas Antibodies  >1 publications with AADAC and Pancreas
 Adrenal Gland Antibodies  >1 publications with AADAC and Adrenal Gland
 Intestine Antibodies  >1 publications with AADAC and Intestine
TOP
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000