Name: AADAC cdna clone-BC032309
Brand: MyBioSource
Price: 165 USD

Product Name

AADAC, cDNA Clone

Full Product Name

AADAC cDNA Clone

Product Gene Name

AADAC cdna clone

[Similar Products]

Research Use Only

For Research Use Only. Not for use in diagnostic procedures.

atgggaagaa aatcgctgta ccttctgatt gtggggatcc tcatagcata ttatatttat acgcctctcc cagataacgt tgaggagcca tggagaatga tgtggataaa cgcacatctg aaaactatac aaaatttggc tacatttgtg gagctcctgg gacttcacca ttttatggat tcctttaagg ttgtcgggag ctttgatgaa gtcccaccaa cctcagatga aaatgtcact gtgactgaga caaaattcaa caacattctt gttcgggtat atgtgccaaa gagaaagtct gaagcactaa gaagggggtt gttttacatc catggtggag gctggtgcgt gggaagtgct gctctaagtg gttatgactt gctgtcaaga tggacagcag acagacttga tgctgtcgtc gtatcaacca actacagatt agcacctaag tatcatttcc caattcaatt tgaagatgta tataatgcct taaggtggtt cttacgtaaa aaagttcttg caaaatatgg tgtgaaccct gagagaatcg gtatttctgg agatagtgca ggagggaatt tagctgcagc agtgactcaa cagctccttg atgacccaga tgtcaagatc aaactcaaga tccagtcttt aatttatcct gcccttcagc ctcttgatgt agatttaccg tcatatcaag aaaattcaaa ttttctattt ctatccaaat cactcatggt cagattctgg agtgaatatt ttaccactga tagatcactt gaaaaagcca tgctttccag acaacatgta cctgtggaat caagtcatct cttcaaattt gttaattgga gttccctgct ccctgagagg tttataaaag gacatgttta taacaatcca aattatggca gttctgagct ggctaaaaaa tatccagggt tcctagatgt gagggcagcc cctttgttgg ctgatgacaa caaattacgt ggcttacccc tgacctatgt catcacctgt caatatgatc tcttaagaga tgatggactc atgtatgtca cccgacttcg caacactggg gttcaggtga ctcataacca tgttgaggat ggattccatg gagcattttc atttctggga cttaaaatta gtcacagact tataaatcag tatattgagt ggctaaagga aaatctatag

OMIM

600338

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of AADAC cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

TOP

NCBI/Uniprot data below describe general gene information for AADAC. It may not necessarily be applicable to this product.

NCBI GI #

21595550

NCBI GeneID

13

NCBI Accession #

BC032309 [Other Products]

UniProt Secondary Accession #

Q8N1A9; A8K3L3; D3DNJ6[Other Products]

UniProt Related Accession #

P22760[Other Products]

Molecular Weight

45,734 Da

TOP

NCBI Official Full Name

Homo sapiens arylacetamide deacetylase (esterase), mRNA

NCBI Official Synonym Full Names

arylacetamide deacetylase

NCBI Official Symbol

AADAC [Similar Products]

NCBI Official Synonym Symbols

DAC; CES5A1

[Similar Products]

NCBI Protein Information

arylacetamide deacetylase

UniProt Protein Name

Arylacetamide deacetylase

Protein Family

Arylacetamide deacetylase

UniProt Gene Name

AADAC [Similar Products]

UniProt Synonym Gene Names

DAC [Similar Products]

UniProt Entry Name

AAAD_HUMAN

TOP

NCBI Summary for AADAC

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]

TOP

UniProt Comments for AADAC

AADAC: Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores. Belongs to the 'GDXG' lipolytic enzyme family.

Protein type: Endoplasmic reticulum; Deacetylase; EC 3.1.1.3; Motility/polarity/chemotaxis; Membrane protein, integral; Lipase

Chromosomal Location of Human Ortholog: 3q25.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: catalytic activity; deacetylase activity; lipase activity; serine hydrolase activity; triacylglycerol lipase activity

Biological Process: xenobiotic metabolic process

Research Articles on AADAC

1. Translational N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.

TOP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

TOP

Diseases associated with AADAC cdna clone

Disease Name	Pubmed Publications
Drug Toxicity Antibodies	>2 publications with AADAC and Drug Toxicity
Hepatitis Antibodies	>1 publications with AADAC and Hepatitis
Carcinoma, Hepatocellular Antibodies	>1 publications with AADAC and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with AADAC and Liver Neoplasms
Fatty Liver Antibodies	>1 publications with AADAC and Fatty Liver
Liver Diseases Antibodies	>1 publications with AADAC and Liver Diseases

Organs/Tissues associated with AADAC cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>13 publications with AADAC and Liver
Adipose Tissue Antibodies	>1 publications with AADAC and Adipose Tissue
Connective Tissue Antibodies	>1 publications with AADAC and Connective Tissue
Pancreas Antibodies	>1 publications with AADAC and Pancreas
Adrenal Gland Antibodies	>1 publications with AADAC and Adrenal Gland
Intestine Antibodies	>1 publications with AADAC and Intestine

Catalog #	MBS1265705
Unit / Price	0.01 mg Plasmid + 0.2 mL Glycerol-Stock / $165 +1 FREE 8GB USB