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AAMP sirna

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Catalog # MBS8231755
Unit / Price
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  15 nmol  /  $365 +1 FREE 8GB USB
  30 nmol  /  $515 +1 FREE 8GB USB
AAMP sirna
Product Name

AAMP, siRNA

Popular Item
Full Product Name

AAMP siRNA (Human)

Product Synonym Names
Angio-associated migratory cell protein
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603488
3D Structure
ModBase 3D Structure for Q13685
Host
Synthetic
Species Reactivity
Human
Specificity
AAMP siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human AAMP gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Other Notes
Small volumes of AAMP sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AAMP sirna
siRNA to inhibit AAMP expression using RNA interference
Applications Tested/Suitable for AAMP sirna
RNA Interference (RNAi)
NCBI/Uniprot data below describe general gene information for AAMP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,751 Da
NCBI Official Full Name
angio-associated migratory cell protein isoform 2
NCBI Official Synonym Full Names
angio-associated, migratory cell protein
NCBI Official Symbol
NCBI Protein Information
angio-associated migratory cell protein
UniProt Protein Name
Angio-associated migratory cell protein
UniProt Gene Name
UniProt Entry Name
AAMP_HUMAN
NCBI Summary for AAMP
The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]
UniProt Comments for AAMP
AAMP: Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.

Protein type: Cell development/differentiation; Cell surface; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cell surface; cytoplasm; plasma membrane

Molecular Function: heparin binding

Biological Process: smooth muscle cell migration; angiogenesis; cell differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with AAMP sirna
 Products by Pathway  Pathway Diagram
 NOD Pathway antibodies  NOD Pathway Diagram
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