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AANAT elisa kit :: Rat arylalkylamine N-acetyltransferase ELISA Kit

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Catalog # MBS9334672
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
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AANAT elisa kit
Product Name

arylalkylamine N-acetyltransferase (AANAT), ELISA Kit

Full Product Name

Rat Serotonin N-acetyltransferase, AANAT ELISA Kit

Product Synonym Names
Rat Serotonin N-acetyltransferase (AANAT) ELISA kit; SNAT; serotonin acetylase; arylalkylamine N-acetyltransferase
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q64666
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of AANAT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for AANATpurchase
MBS9334672 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the arylalkylamine N-acetyltransferase (AANAT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AANAT. The ELISA analytical biochemical technique of the MBS9334672 kit is based on AANAT antibody-AANAT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AANAT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AANAT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for AANAT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,142 Da
NCBI Official Full Name
serotonin N-acetyltransferase
NCBI Official Synonym Full Names
aralkylamine N-acetyltransferase
NCBI Official Symbol
Aanat  [Similar Products]
NCBI Official Synonym Symbols
Nat4; AA-NAT
  [Similar Products]
NCBI Protein Information
serotonin N-acetyltransferase; serotonin acetylase; Seretonin N-acetyltransferase; arylakylamine N-acetyltransferase; arylalkylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase)
UniProt Protein Name
Serotonin N-acetyltransferase
UniProt Synonym Protein Names
Aralkylamine N-acetyltransferase; AA-NAT
UniProt Gene Name
Aanat  [Similar Products]
UniProt Synonym Gene Names
Snat; Serotonin acetylase; AA-NAT  [Similar Products]
UniProt Entry Name
SNAT_RAT
NCBI Summary for AANAT
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014]
UniProt Comments for AANAT
AA-NAT: Catalyzes the N-acetylation of serotonin into N- acetylserotonin. Controls the night/day rhythm of melatonin production in the pineal gland. Has a relative affinity for hydroxylated versus non-hydroxylated arylalkylamines. Belongs to the acetyltransferase family. AANAT subfamily. Monomer. Interacts with YWHAZ; the interaction requires phosphorylation on Thr-31, and modulates the enzymatic activity of AANAT through preventing dephosphorylation and/or proteolysis and stabilizing substrate binding. Subsequently, a second molecule of AANAT can bind, via the phosphorylated Ser-205 site, the other YWHAZ monomer with similar effect.

Protein type: Amino Acid Metabolism - tryptophan; EC 2.3.1.87; Acetyltransferase

Cellular Component: perinuclear region of cytoplasm; cytoplasm

Molecular Function: arylamine N-acetyltransferase activity; aralkylamine N-acetyltransferase activity

Biological Process: circadian rhythm; N-terminal protein amino acid acetylation; response to light stimulus; melatonin biosynthetic process; response to cAMP; response to organic cyclic substance; response to insulin stimulus; entrainment of circadian clock by photoperiod; response to copper ion; response to zinc ion; photoperiodism; response to cytokine stimulus; response to calcium ion; response to corticosterone stimulus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with AANAT elisa kit
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >59 publications with AANAT and Eye
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