• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AARS2 cdna clone

Scan QR to view Datasheet
Catalog # MBS1270089
Unit / Price
Scan QR to view Datasheet
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $845 +1 FREE 8GB USB
AARS2 cdna clone
Product Name

AARS2, cDNA Clone

Full Product Name

AARS2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGGCAGCGT CAGTGGCAGC TGCAGCCCGG AGGCTGCGGC GGGCCATTCG AAGGTCGCCC GCATGGCGGG GCCTCAGCCA TCGGCCGCTC TCATCGGAGC CCCCTGCAGC CAAGGCCTCG GCCGTGAGGG CCGCCTTTCT GAACTTCTTT CGGGACCGCC ATGGCCACCG GCTGGTGCCC TCCGCTTCCG TGCGGCCCCG CGGCGACCCC AGTTTGCTTT TTGTCAATGC GGGCATGAAC CAGTTCAAGC CAATCTTTCT GGGCACCGTG GATCCACGAA GCGAGATGGC AGGCTTCCGA CGTGTGGCCA ACAGCCAGAA ATGTGTGAGA GCTGGAGGAC ACCATAACGA CCTGGAAGAT GTGGGTCGAG ACCTTTCCCA TCATACCTTC TTTGAAATGC TTGGCAATTG GGCCTTTGGG GGTGAATATT TTAAGGAGGA GGCTTGTAAC ATGGCCTGGG AACTGCTGAC TCAGGTCTAT GGGATCCCTG AGGAAAGGCT CTGGATCTCC TACTTTGATG GTGACCCCAA GGCAGGGCTG GACCCAGACC TGGAGACCAG GGACATCTGG CTGAGCTTAG GGGTGCCTGC TAGCCGTGTG CTTTCCTTTG GACCACAAGA GAACTTCTGG GAGATGGGGG ATACTGGCCC TTGTGGGCCC TGTACTGAGA TCCACTACGA CCTTGCTGGT GGGGTGGGAG CCCCCCAGCT GGTAGAGCTT TGGAACCTGG TCTTCATGCA ACACAACAGA GAGGCAGATG GAAGCCTGCA GCCCCTGCCC CAGCGGCATG TGGACACAGG AATGGGCCTG GAAAGGCTGG TGGCTGTGCT GCAAGGCAAA CACTCCACCT ATGACACTGA CCTCTTTTCC CCGCTGCTCA ACGCCATACA GCAGGGCTGC AGGGCACCCC CTTACTTGGG CCGAGTAGGG GTGGCAGACG AGGGGCGCAC AGACACAGCG TACCGCGTGG TGGCTGACCA CATCCGCACA CTCAGTGTCT GCATCTCTGA TGGCGTCTTC CCTGGGATGT CAGGTCCCCC GCTGGTTCTT CGTCGGATCC TGCGTCGAGC TGTGCGTTTC TCCATGGAGA TCTTAAAGGC ACCACCTGGC TTCCTAGGCA GCCTGGTACC TGTAGTGGTG GAGACACTGG GAGATGCTTA TCCAGAACTG CAAAGGAACT CAGCCCAGAT CGCCAACCTG GTGTCAGAGG ACGAGGCAGC CTTCCTGGCC TCCCTGGAGC GGGGTAGGCG GATCATTGAT CGGACTCTGA GGACCCTGGG GCCTTCAGAT ATGTTCCCTG CTGAAGTGGC CTGGTCCTTG TCACTGTGTG GAGACCTGGG ACTCCCCTTG GACATGGTAG AGCTGATGCT GGAGGAGAAA GGGGTCCAGC TAGACTCCGC TGGACTGGAG CGGTTGGCCC AAGAGGAGGC CCAGCACCGG GCACGGCAGG CTGAGCCAGT TCAGAAGCAG GGATTGTGGC TTGATGTCCA TGCGCTTGGG GAGCTGCAGC GCCAAGGAGT GCCCCCAACT GACGACAGCC CCAAGTACAA CTACTCCCTG CGACCCAGCG GAAGTTATGA GTTCGGCACC TGTGAGGCCC AGGTGTTGCA ACTGTATACA GAGGACGGGA CAGCAGTGGC CTCCGTGGGG AAAGGCCAGC GCTGTGGCCT CCTCTTGGAC AGGACCAACT TCTACGCAGA ACAGGGGGGC CAGGCTTCAG ACCGTGGCTA CCTGGTGCGG GCAGGGCAAG AGGACGTGCT GTTCCCAGTA GCCCGGGCCC AGGTCTGTGG AGGTTTCATC CTGCATGAGG CAGTAGCCCC TGAGTGCCTG CGGTTAGGGG ACCAGGTGCA GCTGCATGTG GATGAGGCCT GGCGTCTAGG CTGCATGGCG AAGCATACGG CCACCCACCT GCTGAACTGG GCACTGAGGC AGACCCTGGG CCCTGGCACA GAGCAGCAGG GCTCCCATCT CAATCCTGAG CAGCTGCGCT TGGATGTGAC CACCCAGACC CCATTGACCC CAGAGCAGCT CCGGGCAGTG GAGAACACTG TGCAGGAGGC CGTGGGGCAG GATGAGGCTG TGTACATGGA GGAGGTGCCC CTGGCGCTCA CTGCCCAGGT CCCTGGCCTG CGCTCTCTGG ATGAGGTTTA CCCAGACCCT GTGCGGGTGG TATCAGTGGG GGTGCCCGTG GCCCATGCAT TGGACCCAGC CTCCCAAGCC GCACTGCAGA CCTCTGTGGA GCTATGCTGT GGGACGCACC TGTTACGTAC TGGGGCTGTA GGGGACCTGG TTATCATCGG GGACCGCCAG CTTTCCAAGG GCACTACCCG CCTGCTGGCC GTCACTGGGG AGCAGGCCCA GCAGGCCCGA GAGCTAGGCC AGAGCCTGGC CCAGGAAGTG AAAGCGGCCA CTGAGCGGCT GAGTCTGGGG AGCCGGGATG TGGCGGAGGC ACTGAGGCTG TCCAAGGACA TAGGACGACT CATTGAAGCT GTGGAAACTG CTGTGATGCC CCAGTGGCAG CGGCGGGAGC TGCTGGCCAC AGTGAAGATG CTGCAGCGGC GTGCCAACAC TGCCATCCGT AAGCTGCAAA TGGGACAGGC TGCAAAAAAA ACTCAGGAGC TGCTGGAGCG GCACTCGAAG GGGCCTCTGA TTGTGGACAC AGTCTCTGCT GAGTCTCTCT CAGTGCTGGT GAAGGTGGTA CGGCAGCTGT GTGAGCAGGC CCCCAGCACG TCTGTGCTCC TACTCAGCCC CCAGCCCATG GGGAAGGTGC TGTGTGCCTG TCAGGTGGCC CAGGGTGCCA TGCCCACCTT CACAGCAGAG GCCTGGGCAC TGGCAGTGTG CAGCCACATG GGGGGCAAGG CGTGGGGCTC GCGAGTGGTG GCCCAAGGCA CCGGAAGCAC TACTGACCTG GAAGCTGCCC TCAGTATAGC CCAAACCTAT GCCCTCAGCC AGCTCTGA
OMIM
612035
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AARS2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AARS2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
107,340 Da
NCBI Official Full Name
Homo sapiens alanyl-tRNA synthetase 2, mitochondrial (putative), mRNA
NCBI Official Synonym Full Names
alanyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
AARS2  [Similar Products]
NCBI Official Synonym Symbols
AARSL; LKENP; COXPD8; MTALARS; MT-ALARS
  [Similar Products]
NCBI Protein Information
alanine--tRNA ligase, mitochondrial
UniProt Protein Name
Alanine--tRNA ligase, mitochondrial
UniProt Synonym Protein Names
Alanyl-tRNA synthetase
UniProt Gene Name
AARS2  [Similar Products]
UniProt Synonym Gene Names
AlaRS  [Similar Products]
UniProt Entry Name
SYAM_HUMAN
NCBI Summary for AARS2
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]
UniProt Comments for AARS2
AARSL: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Defects in AARS2 are the cause of combined oxidative phosphorylation deficiency type 8 (COXPD8). A mitochondrial disease characterized by a lethal infantile hypertrophic cardiomyopathy, generalized muscle dysfunction and some neurologic involvement. The liver is not affected. Belongs to the class-II aminoacyl-tRNA synthetase family.

Protein type: Translation; EC 6.1.1.7; Ligase

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: cytosol; mitochondrion

Molecular Function: alanine-tRNA ligase activity; amino acid binding; tRNA binding

Biological Process: mitochondrial respiratory chain complex assembly; tRNA modification

Disease: Combined Oxidative Phosphorylation Deficiency 8; Leukoencephalopathy, Progressive, With Ovarian Failure
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000