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AATK blocking peptide

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Catalog # MBS9230027
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
AATK blocking peptide
Product Name

AATK, Blocking Peptide

Also Known As

AATK Blocking Peptide (N-Term)

Product Synonym Names
Serine/threonine-protein kinase LMTK1; Apoptosis-associated tyrosine kinase; AATYK; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP; AATK; AATYK; KIAA0641; LMR1; LMTK1
Product Synonym Gene Name
AATYK; KIAA0641; LMR1; LMTK1[Similar Products]
Antibody/Peptide Pairs
AATK peptide (MBS9230027) is used for blocking the activity of AATK antibody (MBS9206001)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1374
OMIM
605276
3D Structure
ModBase 3D Structure for Q6ZMQ8
Specificity
The synthetic peptide sequence is selected from aa 55-70 of HUMAN AATK
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note: Predominantly perinuclear
Tissue Location
Expressed in brain.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of AATK blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AATK blocking peptide
May be involved in neuronal differentiation.
NCBI/Uniprot data below describe general gene information for AATK. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
93,226 Da
NCBI Official Full Name
Serine/threonine-protein kinase LMTK1
NCBI Official Synonym Full Names
apoptosis associated tyrosine kinase
NCBI Official Symbol
NCBI Official Synonym Symbols
LMR1; AATYK; LMTK1; p35BP; AATYK1; PPP1R77
  [Similar Products]
NCBI Protein Information
serine/threonine-protein kinase LMTK1
UniProt Protein Name
Serine/threonine-protein kinase LMTK1
UniProt Synonym Protein Names
Apoptosis-associated tyrosine kinase; AATYK; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP
UniProt Gene Name
UniProt Synonym Gene Names
AATYK; KIAA0641; LMR1; LMTK1; AATYK; p35BP  [Similar Products]
UniProt Entry Name
LMTK1_HUMAN
NCBI Summary for AATK
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for AATK
Lmr1: a protein kinase kinase of the Lmr family. Predominantly expressed in the nervous system and is involved in neurite extension and apoptosis of cerebellar granule cells. Contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. May be necessary for the induction of growth arrest and/or apoptosis of myeloid cells induced by cytokine withdrawal, such as IL3, and during G-CSF-induced terminal differentiation of myeloblasts to granulocytes. Four alternatively spliced isoforms have been reported.

Protein type: Membrane protein, integral; EC 2.7.11.1; Kinase, protein; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Lmr family

Chromosomal Location of Human Ortholog: 17q25.3
Research Articles on AATK
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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