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ABCA3 cdna clone

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Catalog # MBS1274144
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ABCA3 cdna clone
Product Name

ABCA3, cDNA Clone

Full Product Name

ABCA3 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctgtgc tcaggcagct ggcgctcctc ctctggaaga actacaccct gcagaagcgg aaggtcctgg tgacggtcct ggaactcttc ctgccattgc tgttttctgg gatcctcatc tggctccgct tgaagattca gtcggaaaat gtgcccaacg ccaccatcta cccgggccag tccatccagg agctgcctct gttcttcacc ttccctccgc caggagacac ctgggagctt gcctacatcc cttctcacag tgacgctgcc aagaccgtca ctgagacagt gcgcagggca cttgtgatca acatgcgagt gcgcggcttt ccctccgaga aggactttga ggactacatt aggtacgaca actgctcgtc cagcgtgctg gccgccgtgg tcttcgagca ccccttcaac cacagcaagg agcccctgcc gctggcggtg aaatatcacc tacggttcag ttacacacgg agaaattaca tgtggaccca aacaggctcc tttttcctga aagagacaga aggctggcac actacttccc ttttcccgct tttcccaaac ccaggaccaa gggaacctac atcccctgat ggcggagaac ctggtgagaa gctcggttag
OMIM
601615
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ABCA3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCA3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,002 Da
NCBI Official Full Name
Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3, mRNA
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 3
NCBI Official Symbol
ABCA3  [Similar Products]
NCBI Official Synonym Symbols
ABC3; ABC-C; SMDP3; LBM180; EST111653
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family A member 3
UniProt Protein Name
ATP-binding cassette sub-family A member 3
UniProt Synonym Protein Names
ABC-C transporter; ATP-binding cassette transporter 3; ATP-binding cassette 3
Protein Family
UniProt Gene Name
ABCA3  [Similar Products]
UniProt Synonym Gene Names
ABC3; ATP-binding cassette 3  [Similar Products]
UniProt Entry Name
ABCA3_HUMAN
NCBI Summary for ABCA3
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA3
ABCA3: Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3); also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the ABC transporter superfamily. ABCA family.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space; membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; lipid transporter activity; transporter activity

Biological Process: cellular protein metabolic process; lipid transport; response to drug; transmembrane transport; transport

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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