NP_525022.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,998 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 9
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 9
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-binding cassette sub-family A member 9
UniProt Protein Name
ATP-binding cassette sub-family A member 9
UniProt Entry Name
ABCA9_HUMAN
NCBI Summary for ABCA9
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA9
ABCA9: May play a role in monocyte differentiation and lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Membrane protein, integral; Transporter, ABC family; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: integral to membrane; mitochondrial inner membrane
Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances
Biological Process: lipid transport; metabolic process; transmembrane transport
Research Articles on ABCA9
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Pathways associated with ABCA9 blocking peptide
Diseases associated with ABCA9 blocking peptide
Organs/Tissues associated with ABCA9 blocking peptide
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