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ABCB7 cdna clone

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Catalog # MBS1269782
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $650 +1 FREE 8GB USB
ABCB7 cdna clone
Product Name

ABCB7, cDNA Clone

Full Product Name

ABCB7 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcgctgc tcgcgatgca ttcttggcgc tgggcggccg cggcggctgc tttcgaaaag cgccggcact ccgcgattct gatccggcct ttagtctctg ttagcggctc aggtccgcag tggaggccac atcaactcgg cgccttggga accgctcgag cctaccagca gattccagag tcattaaaaa gtatcacatg gcagagattg ggaaaaggca attcaggaca gttcttagat gctgcaaagg ctctccaggt atggccactg atagaaaaga ggacatgttg gcatggtcat gcaggaggag gactccacac agacccaaaa gaagggttaa aagatgttga tactcggaaa atcataaaag caatgctttc ttatgtgtgg cccaaagaca ggccagatct acgagctaga gttgccattt cgctgggatt tttgggtggt gcaaaggcca tgaatattgt ggttcccttc atgtttaaat atgctgtaga cagcctcaac cagatgtcgg gaaacatgct gaacctgagt gatgcaccaa atacagttgc aaccatggca acagcagttc tgattggcta tggtgtatca agagctggag ctgctttttt taacgaagtt cgaaatgcag tatttggcaa ggtagcccag aattcaatcc gaagaatagc caaaaatgtc tttctccatc ttcacaacct ggatctgggt tttcacctga gcagacagac gggagcttta tctaaggcta ttgacagagg aacaaggggt atcagttttg tcctgagtgc tttggtattt aatcttcttc ccatcatgtt tgaagtgatg cttgtcagtg gtgttttgta ttacaaatgc ggtgcccagt ttgctttggt aacccttgga acacttggta catacacagc attcacagtt gcagtcacac ggtggagaac tagatttaga atagaaatga acaaagcaga taatgatgca ggtaatgctg ctatagactc actgctgaat tatgaaactg tgaagtattt taataatgaa agatatgaag cacagagata tgatggattt ttgaagacgt atgagactgc ttcattgaaa agtacctcta ctctggctat gctgaacttt ggtcaaagtg ctattttcag tgtcggttta acagctataa tggtgctcgc cagtcaggga attgtggcag gtacccttac tgttggagat ctagtaatgg tgaatggact gctttttcag ctttcattac ccctgaactt tctgggaact gtatatagag agactagaca agcactcata gatatgaaca ccttgtttac tctactcaag gtagacaccc aaattaaaga caaagtgatg gcatctcccc ttcagatcac accacagaca gctaccgtgg cctttgataa tgtgcatttt gaatacattg agggccagaa agtccttagt ggaatatcct ttgaagtccc tgcaggaaag aaagtggcca ttgtaggagg tagtgggtca gggaaaagca caatagtgag gctattattt cgcttctatg agcctcaaaa gggtagcatt tatcttgctg gtcaaaatat acaagatgtg agcctggaaa gccttcggag ggcagtggga gtggtacctc aggatgctgt cctcttccat aatactattt attacaacct cttatatgga aacatcagtg cttcacctga ggaagtgtat gcagtggcaa aattagctgg acttcatgat gcaattcttc gaatgccaca tggatatgac acccaagtag gggaacgagg actcaagctt tcaggaggag aaaagcaaag agtagcaatt gcaagagcca ttttgaagga ccccccagtc atactctatg atgaagctac ttcatcgtta gattcgatta ctgaagagac tattcttggt gccatgaagg atgtggtcaa acacagaact tctattttca ttgcacacag attgtcaaca gtggttgatg cagatgaaat cattgtcttg gatcagggta aggtagccga acgtggtacc caccatggtt tgcttgctaa ccctcatagt atctattcag aaatgtggca tacacagagc agccgtgtgc agaaccatga taaccccaaa tgggaagcaa agaaagaaaa tatatccaaa gaggaggaaa gaaagaaact acaagaagaa attgtcaata gtgtgaaagg ctgtggaaac tgttcgtgct aa
OMIM
300135
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ABCB7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCB7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,160 Da
NCBI Official Full Name
Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 7, mRNA
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 7
NCBI Official Symbol
ABCB7  [Similar Products]
NCBI Official Synonym Symbols
ABC7; ASAT; Atm1p; EST140535
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 7, mitochondrial
UniProt Protein Name
ATP-binding cassette sub-family B member 7, mitochondrial
UniProt Synonym Protein Names
ATP-binding cassette transporter 7; ABC transporter 7 protein
Protein Family
UniProt Gene Name
ABCB7  [Similar Products]
UniProt Synonym Gene Names
ABC7; ABC transporter 7 protein  [Similar Products]
UniProt Entry Name
ABCB7_HUMAN
NCBI Summary for ABCB7
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
UniProt Comments for ABCB7
ABCB7: Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins. Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT). ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis. Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter; Mitochondrial; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: Xq13.3

Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion

Molecular Function: heme transporter activity

Biological Process: cellular iron ion homeostasis; transmembrane transport; transport

Disease: Anemia, Sideroblastic, And Spinocerebellar Ataxia
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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