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ABCC11 cdna clone

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Catalog # MBS1268541
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
ABCC11 cdna clone
Product Name

ABCC11, cDNA Clone

Full Product Name

ABCC11 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgactagga agaggacata ctgggtgccc aactcttctg gtggcctcgt gaatcgtggc atcgacatag gcgatgacat ggtttcagga cttatttata aaacctatac tctccaagat ggcccctgga gtcagcaaga gagaaatcct gaggctccag ggagggcagc tgtcccaccg tgggggaagt atgatgctgc cttgagaacc atgattccct tccgtcccaa gccgaggttt cctgcccccc agcccctgga caatgctggc ctgttctcct acctcaccgt gtcatggctc accccgctca tgatccaaag cttacggagt cgcttagatg agaacaccat ccctccactg tcagtccatg atgcctcaga caaaaatgtc caaaggcttc accgcctttg ggaagaagaa gtctcaaggc gagggattga aaaagcttca gtgcttctgg tgatgctgag gttccagaga acaaggttga ttttcgatgc acttctgggc atctgcttct gcattgccag tgtactcggg ccaatattga ttataccaaa gatcctggaa tattcagaag agcagttggg gaatgttgtc catggagtgg gactctgctt tgcccttttt ctctccgaat gtgtgaagtc tctgagtttc tcctccagtt ggatcatcaa ccaacgcaca gccatcaggt tccgagcagc tgtttcctcc tttgcctttg agaagctcat ccaatttaag tctgtaatac acatcacctc aggagaggcc atcagcttct tcaccggtga tgtaaactac ctgtttgaag gggtgtgcta tggaccccta gtactgatca cctgcgcatc gctggtcatc tgcagcattt cttcctactt cattattgga tacactgcat ttattgccat cttatgctat ctcctggttt tcccactggc ggtattcatg acaagaatgg ctgtgaaggc tcagcatcac acatctgagg tcagcgacca gcgcatccgt gtgaccagtg aagttctcac ttgcattaag ctgattaaaa tgtacacatg ggagaaacca tttgcaaaaa tcattgaaga cctaagaagg aaggaaagga aactattgga gaagtgcggg cttgtccaga gcctgacaag tataaccttg ttcatcatcc ccacagtggc cacagcggtc tgggttctca tccacacatc cttaaagctg aaactcacag cgtcaatggc cttcagcatg ctggcctcct tgaatctcct tcggctgtca gtgttctttg tgcctattgc agtcaaaggt ctcacgaatt ccaagtctgc agtgatgagg ttcaagaagt ttttcctcca ggagagccct gttttctatg tccagacatt acaagacccc agcaaagctc tggtctttga ggaggccacc ttgtcatggc aacagacctg tcccgggatc gtcaatgggg cactggagct ggagaggaac gggcatgctt ctgaggggat gaccaggcct agagatgccc tcgggccaga ggaagaaggg aacagcctgg gcccagagtt gcacaagatc aacctggtgg tgtccaaggt agccttgttc aggccacgca ggcaggccag ctgccaggct ctcaggacct ga
OMIM
117800
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ABCC11 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCC11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
150,093 Da
NCBI Official Full Name
Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 11, mRNA
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 11
NCBI Official Symbol
ABCC11  [Similar Products]
NCBI Official Synonym Symbols
WW; EWWD; MRP8
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family C member 11
UniProt Protein Name
ATP-binding cassette sub-family C member 11
UniProt Synonym Protein Names
Multidrug resistance-associated protein 8
Protein Family
UniProt Gene Name
ABCC11  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
ABCCB_HUMAN
NCBI Summary for ABCC11
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCC11
ABCC11: Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter; Transporter, ABC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: anion transmembrane-transporting ATPase activity; organic anion transmembrane transporter activity; purine nucleotide transmembrane transporter activity

Biological Process: organic anion transport; purine nucleotide transport; transmembrane transport

Disease: Apocrine Gland Secretion, Variation In
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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