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ABCC3 blocking peptide

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Catalog # MBS9217445
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
ABCC3 blocking peptide
Product Name

ABCC3, Blocking Peptide

Also Known As

ABCC3 Antibody (Center) Blocking peptide

Product Synonym Names
Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3; ABCC3; CMOAT2; MLP2; MRP3
Product Synonym Gene Name
CMOAT2; MLP2; MRP3[Similar Products]
Antibody/Peptide Pairs
ABCC3 peptide (MBS9217445) is used for blocking the activity of ABCC3 antibody (MBS9207382)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1527
OMIM
604323
3D Structure
ModBase 3D Structure for O15438
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Multi-pass membrane protein.
Tissue Location
Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ABCC3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABCC3 blocking peptide
May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).
NCBI/Uniprot data below describe general gene information for ABCC3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,632 Da
NCBI Official Full Name
canalicular multispecific organic anion transporter 2 isoform 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 3
NCBI Official Symbol
ABCC3  [Similar Products]
NCBI Official Synonym Symbols
MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
  [Similar Products]
NCBI Protein Information
canalicular multispecific organic anion transporter 2
UniProt Protein Name
Canalicular multispecific organic anion transporter 2
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3
Protein Family
UniProt Gene Name
ABCC3  [Similar Products]
UniProt Synonym Gene Names
CMOAT2; MLP2; MRP3; MOAT-D  [Similar Products]
UniProt Entry Name
MRP3_HUMAN
NCBI Summary for ABCC3
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCC3
ABCC3: May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: membrane; plasma membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATPase activity, coupled to transmembrane movement of substances; bile acid-exporting ATPase activity; organic anion transmembrane transporter activity

Biological Process: bile acid and bile salt transport; transmembrane transport; transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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