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ABCC4 blocking peptide

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Catalog # MBS9226887
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
ABCC4 blocking peptide
Product Name

ABCC4, Blocking Peptide

Also Known As

ABCC4 Antibody (C-term) Blocking Peptide

Product Synonym Names
Multidrug resistance-associated protein 4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; ABCC4; MRP4
Product Synonym Gene Name
Antibody/Peptide Pairs
ABCC4 peptide (MBS9226887) is used for blocking the activity of ABCC4 antibody (MBS9205055)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1325
OMIM
605250
3D Structure
ModBase 3D Structure for O15439
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human ABCC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Multi-pass membrane protein.
Tissue Location
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ABCC4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABCC4 blocking peptide
May be an organic anion pump relevant to cellular detoxification.
NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
88,138 Da
NCBI Official Full Name
Multidrug resistance-associated protein 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 4
NCBI Official Symbol
ABCC4  [Similar Products]
NCBI Official Synonym Symbols
MRP4; MOATB; MOAT-B
  [Similar Products]
NCBI Protein Information
multidrug resistance-associated protein 4
UniProt Protein Name
Multidrug resistance-associated protein 4
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
Protein Family
UniProt Gene Name
ABCC4  [Similar Products]
UniProt Synonym Gene Names
MRP4; MOAT-B  [Similar Products]
UniProt Entry Name
MRP4_HUMAN
NCBI Summary for ABCC4
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
UniProt Comments for ABCC4
ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: basolateral plasma membrane; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

Biological Process: cilium biogenesis; platelet degranulation; prostaglandin secretion; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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