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ABCD3 peptide

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Catalog # MBS425530
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
ABCD3 peptide
Product Name

ABCD3, Peptide

Popular Item
Also Known As

ABCD3 Immunizing Peptide

Product Synonym Names
ABCD3; ATP-binding cassette, sub-family D (ALD), member 3; ABC43; PMP70; PXMP1; ATP-binding cassette, sub-family D, member 3; Peroxisomal membrane protein-1 (70kD); dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); peroxisoma; ABCD3
Product Gene Name
Antibody/Peptide Pairs
ABCD3 peptide (MBS425530) is used for blocking the activity of ABCD3 antibody (MBS421942)
Antibody/Peptide Pairs
ABCD3 peptide (MBS425530) is used for blocking the activity of ABCD3 antibody (MBS423686)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
659
Sequence
C-PDGREDQK RKGISD
OMIM
170995
Species Reactivity
Human, Mouse, Rat
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of ABCD3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCD3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,121 Da
NCBI Official Full Name
ATP-binding cassette sub-family D member 3 isoform a
NCBI Official Synonym Full Names
ATP binding cassette subfamily D member 3
NCBI Official Symbol
ABCD3  [Similar Products]
NCBI Official Synonym Symbols
ZWS2; ABC43; CBAS5; PMP70; PXMP1
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family D member 3
UniProt Protein Name
ATP-binding cassette sub-family D member 3
UniProt Synonym Protein Names
70 kDa peroxisomal membrane protein; PMP70
Protein Family
UniProt Gene Name
ABCD3  [Similar Products]
UniProt Synonym Gene Names
PMP70; PXMP1; PMP70  [Similar Products]
UniProt Entry Name
ABCD3_HUMAN
NCBI Summary for ABCD3
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCD3
ABCD3: a member of the superfamily of ATP-binding cassette (ABC) transporters. Likely plays an important role in peroxisome biogenesis. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. Defects in ABCD3 may be the cause of Zellweger syndrome-2 (ZWS-2), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes.

Protein type: Membrane protein, integral; Transporter, ABC family; Membrane protein, multi-pass; Mitochondrial; Transporter

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: cytosol; integral to membrane; intracellular membrane-bound organelle; membrane; mitochondrial inner membrane; peroxisomal matrix; peroxisomal membrane; peroxisome

Molecular Function: ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; long-chain fatty acid transporter activity; protein binding; protein homodimerization activity; protein self-association

Biological Process: fatty acid beta-oxidation; fatty acid biosynthetic process; peroxisomal long-chain fatty acid import; peroxisome organization and biogenesis; response to drug; response to organic cyclic substance; transmembrane transport; very-long-chain fatty acid catabolic process

Disease: Bile Acid Synthesis Defect, Congenital, 5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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