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ABCE1 cdna clone

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Catalog # MBS1278091
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
ABCE1 cdna clone
Product Name

ABCE1, cDNA Clone

Full Product Name

ABCE1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcagaca agttaacgag aattgctatt gtcaaccatg acaaatgtaa acctaagaaa tgtcgacagg aatgcaaaaa gagttgtcct gtagttcgaa tgggaaaatt atgcatagag gttacacccc agagcaaaat agcatggatt tccgaaactc tttgtattgg ttgtggtatc tgtattaaga aatgcccctt tggcgcctta tcaattgtca atctaccaag caacttggaa aaagaaacca cacatcgata ttgtgccaat gccttcaaac ttcacaggtt gcctatccct cgtccaggtg aagttttggg attagttgga actaatggta ttggaaagtc aactgcttta aaaattttag caggaaaaca aaagccaaac cttggaaagt acgatgatcc tcctgactgg caggagattt tgacttattt ccgtggatct gaattacaaa attactttac aaagattcta gaagatgacc taaaagccat catcaaacct caatatgtag accagattcc taaggctgca aaggggacag tgggatctat tttggaccga aaagatgaaa caaagacaca ggcaattgta tgtcagcagc ttgatttaac ccacctaaaa gaacgaaatg ttgaagatct ttcaggagga gagttgcaga gatttgcttg tgctgtcgtt tgcatacaga aagctgatat tttcatgttt gatgagcctt ctagttacct agatgtcaag cagcgtttaa aggctgctat tactatacga tctctaataa atccagatag atatatcatt gtggtggaac atgatctaag tgtattagac tatctctccg acttcatctg ctgtttatat ggtgtaccaa gcgcctatgg agttgtcact atgcctttta gtgtaagaga aggcataaac atttttttgg atggctatgt tccaacagaa aacttgagat tcagagatgc atcacttgtt tttaaagtgg ctgagacagc aaatgaagaa gaagttaaaa agatgtgtat gtataaatat ccaggaatga agaaaaaaat gggagaattt gagctagcaa ttgtagctgg agagtttaca gattctgaaa ttatggtgat gctgggggaa aatggaacgg gtaaaacgac atttatcaga atgcttgctg gaagacttaa acctgatgaa ggaggagaag taccagttct aaatgtcagt tataagccac agaaaattag tcccaaatca actggaagtg ttcgccagtt actacatgaa aagataagag atgcttatac tcacccacaa tttgtgaccg atgtaatgaa gcctctgcaa attgaaaaca tcattgatca agaggtgcag acattatctg gtggtgaact acagcgagta gctttagccc tttgcttggg caaacctgct gatgtctatt taattgatga accatctgca tatttggatt ctgagcaaag actgatggca gctcgagttg tcaaacgttt catactccat gcaaaaaaga cagcctttgt tgtggaacat gacttcatca tggccaccta tctagcggat cgcgtcatcg tttttgatgg tgttccatct aagaacacag ttgcaaacag tcctcaaacc cttttggctg gcatgaataa atttttgtct cagcttgaaa ttacattcag aagagatcca aacaactata ggccacgaat aaacaaactt aattcaatta aggatgtaga acaaaagaag agtggaaact actttttctt ggatgattag
OMIM
601213
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ABCE1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCE1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,314 Da
NCBI Official Full Name
Homo sapiens ATP-binding cassette, sub-family E (OABP), member 1, mRNA
NCBI Official Synonym Full Names
ATP binding cassette subfamily E member 1
NCBI Official Symbol
ABCE1  [Similar Products]
NCBI Official Synonym Symbols
RLI; OABP; RLI1; ABC38; RNS4I; RNASEL1; RNASELI
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family E member 1
UniProt Protein Name
ATP-binding cassette sub-family E member 1
UniProt Synonym Protein Names
2'-5'-oligoadenylate-binding protein; HuHP68; RNase L inhibitor; Ribonuclease 4 inhibitor; RNS4I
Protein Family
UniProt Gene Name
ABCE1  [Similar Products]
UniProt Synonym Gene Names
RLI; RNASEL1; RNASELI; RNS4I; RNS4I  [Similar Products]
UniProt Entry Name
ABCE1_HUMAN
NCBI Summary for ABCE1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCE1
ABCE1: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. Belongs to the ABC transporter superfamily. ABCE family.

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: cytoplasm; eukaryotic translation initiation factor 3 complex; membrane; mitochondrial matrix; mitochondrion

Molecular Function: ATP binding; iron ion binding; protein binding; ribosomal small subunit binding

Biological Process: ribosome export from nucleus; translational initiation; translational termination; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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