• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ABCG1 clia kit :: Human ABCG1 (ATP Binding Cassette Transporter G1) CLIA Kit

Scan QR to view Datasheet
Catalog # MBS2530936
Unit / Price
  48-Strip-Wells  /  $450 +1 FREE 8GB USB
  96-Strip-Wells  /  $535 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
  10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

ABCG1 (ATP Binding Cassette Transporter G1), CLIA Kit

Full Product Name

Human ABCG1 (ATP Binding Cassette Transporter G1) CLIA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
603076
Species Reactivity
Specificity
This kit recognizes natural and recombinant ABCG1. No significant cross-reactivity or interference between ABCG1 and analogues was observed.
Assay Type
Sandwich
Detection Range
31.25-2000pg/mL
Sensitivity
Min: 18.75pg/mL; Max: 2000pg/mL
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ABCG1 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABCG1 clia kit
Intended Uses: This CLIA kit applies to the in vitro quantitative determination of ABCG1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to ABCG1. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ABCG1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ABCG1, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of ABCG1. You can calculate the concentration of ABCG1 in the samples by comparing the RLU value of the samples to the standard curve.

Typical Testing Data/Standard Curve (for reference only) of ABCG1 clia kit
ABCG1 clia kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS2530936. Click to request current manual
NCBI/Uniprot data below describe general gene information for ABCG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
86,628 Da
NCBI Official Full Name
ATP-binding cassette transporter G1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 1
NCBI Official Symbol
ABCG1  [Similar Products]
NCBI Official Synonym Symbols
ABC8; WHITE1
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family G member 1
UniProt Protein Name
ATP-binding cassette sub-family G member 1
UniProt Synonym Protein Names
ATP-binding cassette transporter 8; White protein homolog
Protein Family
UniProt Gene Name
ABCG1  [Similar Products]
UniProt Synonym Gene Names
ABC8; WHT1  [Similar Products]
UniProt Entry Name
ABCG1_HUMAN
NCBI Summary for ABCG1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCG1
ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endoplasmic reticulum membrane; endosome; external side of plasma membrane; Golgi apparatus; Golgi membrane; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; mitochondrion; nucleoplasm; plasma membrane; recycling endosome

Molecular Function: ADP binding; ATP binding; cholesterol binding; cholesterol transporter activity; phospholipid binding; phospholipid transporter activity; protein binding; protein dimerization activity; protein heterodimerization activity; protein homodimerization activity; sterol-transporting ATPase activity; toxin transporter activity

Biological Process: amyloid precursor protein catabolic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; detection of hormone stimulus; intracellular cholesterol transport; lipoprotein metabolic process; phospholipid efflux; phospholipid homeostasis; positive regulation of cholesterol biosynthetic process; regulation of transcription, DNA-dependent; response to high density lipoprotein stimulus; response to lipid; response to organic substance; reverse cholesterol transport; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000