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ABCG1 blocking peptide

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Catalog # MBS823933
Unit / Price
  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
ABCG1 blocking peptide
Product Name

ABCG1, Blocking Peptide

Also Known As

ABCG1 Blocking Peptide

Product Synonym Names
ABC8; WHT1; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog
Antibody/Peptide Pairs
ABCG1 peptide (MBS823933) is used for blocking the activity of ABCG1 antibody (MBS820666)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
678
OMIM
603076
3D Structure
ModBase 3D Structure for P45844
Host
Synthetic
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of ABCG1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABCG1 blocking peptide
The peptide is used to block Anti-ABCG1 Antibody reactivity.
Applications Tested/Suitable for ABCG1 blocking peptide
Blocking (BL)
Application Notes for ABCG1 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for ABCG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
86,628 Da
NCBI Official Full Name
ATP-binding cassette sub-family G member 1 isoform 4
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 1
NCBI Official Symbol
ABCG1  [Similar Products]
NCBI Official Synonym Symbols
ABC8; WHITE1
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family G member 1; ABC transporter 8; homolog of Drosophila white; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; white protein homolog (ATP-binding cassette transporter 8)
UniProt Protein Name
ATP-binding cassette sub-family G member 1
UniProt Synonym Protein Names
ATP-binding cassette transporter 8; White protein homolog
Protein Family
UniProt Gene Name
ABCG1  [Similar Products]
UniProt Synonym Gene Names
ABC8; WHT1  [Similar Products]
UniProt Entry Name
ABCG1_HUMAN
NCBI Summary for ABCG1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCG1
ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; recycling endosome; endoplasmic reticulum membrane; mitochondrion; intracellular membrane-bound organelle; integral to plasma membrane; plasma membrane; endosome; external side of plasma membrane

Molecular Function: protein dimerization activity; protein binding; protein homodimerization activity; phospholipid transporter activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; toxin transporter activity; sterol-transporting ATPase activity; phospholipid binding; ADP binding; ATP binding

Biological Process: response to organic substance; cholesterol metabolic process; cholesterol homeostasis; amyloid precursor protein catabolic process; reverse cholesterol transport; detection of hormone stimulus; response to high density lipoprotein stimulus; regulation of transcription, DNA-dependent; phospholipid efflux; positive regulation of cholesterol biosynthetic process; cholesterol efflux; intracellular cholesterol transport; lipoprotein metabolic process; response to lipid; transmembrane transport; phospholipid homeostasis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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