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ABCG8 cdna clone

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Catalog # MBS1274421
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ABCG8 cdna clone
Product Name

ABCG8, cDNA Clone

Popular Item
Full Product Name

ABCG8 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
atggccggga aggcggcaga ggagagaggg ctgccgaaag gggccactcc ccagcatacc tcgggcctcc aggatagatt gttctcctct gaaagtgaca acagcctgta cttcacctac agtggccagc ccaacaccct ggaggtcaga gacctcaact accaggtgga cctggcctct caggtccctt ggtttgagca gctggctcag ttcaagatgc cctggacatc tcccagctgc cagaattctt gtgagctggg catccagaac ctaagcttca aagtgagaag tgggcagatg ctggccatca tagggagctc aggttgtggg agagcctcct tgctagatgt gatcactggc cgaggtcacg gcggcaagat caagtcaggc cagatctgga tcaatgggca gcccagctcg cctcagctgg tgaggaagtg tgtggcccac gtgcgccagc acaaccagct gctccccaac ttgactgtgc gagagacctt ggccttcatt gcccagatgc ggctgcccag aaccttctcc caggcccagc gtgacaaaag ggtggaggac gtgatcgcgg agctgcggct taggcagtgc gctgacaccc gcgtgggcaa catgtacgtg cgggggttgt cggggggtga gcgcaggaga gtcagcattg gggtgcagct cctgtggaac ccaggaatcc ttattctcga cgaacccacc tctgggctcg acagcttcac agcccacaac ctggtgaaga ccttgtccag gctggccaaa ggcaaccggc tggtgctcat ctccctccac cagcctcgct ctgacatctt caggctgttt gatctggtcc tcctgatgac gtctggcacc cccatctact taggggcggc ccagcacatg gtccagtatt tcacagccat cggctacccc tgtcctcgct acagcaatcc tgctgacttc tatgtggacc tgaccagcat tgacaggcgc agcagagagc aggaattggc caccagggag aaggctcagt cactcgcagc cctgtttcta gaaaaagtgc gtgacttaga tgactttcta tggaaagcag agacgaagga tcttgacgag gacacctgtg tggaaagcag cgtgacccca ctagacacca actgcctccc gagtcctacg aagatgcctg gggcggtgca gcagtttacg acgctgatcc gtcgtcagat ttccaacgac ttccgagacc tgcccaccct cctcatccat ggggcggagg cctgtctgat gtcaatgacc atcggcttcc tctattttgg ccatgggagc atccagctct ccttcatgga tacagccgcc ctcttgttca tgatcggtgc tctcatccct ttcaacgtca ttctggatgt catctccaaa tgttactcag agagggcaat gctttactat gaactggaag acgggctgta caccactggt ccatatttct ttgccaagat cctcggggag cttccggagc actgtgccta catcatcatc tacgggatgc ccacctactg gctggccaac ctgaggccag gcctccagcc cttcctgctg cacttcctgc tggtgtggct ggtggtcttc tgttgcagga ttatggccct ggccgccgcg gccctgctcc ccaccttcca catggcctcc ttcttcagca atgccctcta caactccttc tacctcgccg ggggcttcat gataaacttg agcagcctgt ggacagtgcc cgcgtggatt tccaaagtgt ccttcctgcg gtggtgtttt gaagggctga tgaagattca gttcagcaga agaacttata aaatgcctct cgggaacctc accatcgcgg tctcaggaga taaaatcctc agtgccatgg agctggactc gtaccctctc tacgccatct acctcatcgt cattggcctc agcggtggct tcatggtcct gtactacgtg tccttaaggt tcatcaaaca gaaaccaagt caagactggt ga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ABCG8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABCG8. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,592 Da
NCBI Official Full Name
Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 8, mRNA
NCBI Official Synonym Full Names
ATP binding cassette subfamily G member 8
NCBI Official Symbol
ABCG8  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family G member 8
UniProt Protein Name
ATP-binding cassette sub-family G member 8
UniProt Synonym Protein Names
Protein Family
UniProt Gene Name
ABCG8  [Similar Products]
UniProt Entry Name
NCBI Summary for ABCG8
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCG8
ABCG8: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Genetic variations in ABCG8 can be associated with susceptibility to gallbladder disease type 4 (GBD4). With an overall prevalence of 10-20%, gallstone disease (cholelithiasis) represents one of the most frequent and economically relevant health problems of industrialized countries. Defects in ABCG8 are a cause of sitosterolemia (STSL); also known as phytosterolemia or shellfish sterolemia. It is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile. Sitosterolemia patients have hypercholesterolemia, very high levels of plant sterols in the plasma, and frequently develop tendon and tuberous xanthomas, accelerated atherosclerosis and premature coronary artery disease. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, ABC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: apical plasma membrane; ATP-binding cassette (ABC) transporter complex; plasma membrane; receptor complex

Molecular Function: ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; cholesterol transporter activity; protein binding; protein heterodimerization activity

Biological Process: cholesterol absorption; cholesterol efflux; cholesterol homeostasis; excretion; negative regulation of cholesterol absorption; sterol transport; transmembrane transport

Disease: Gallbladder Disease 4; Sitosterolemia
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Organs/Tissues associated with ABCG8 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with ABCG8 and Muscle
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