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ABHD5 cdna clone

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Catalog # MBS1270838
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ABHD5 cdna clone
Product Name

ABHD5, cDNA Clone

Full Product Name

ABHD5 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
atggcggcgg aggaggagga ggtggactct gccgacaccg gagagaggtc aggatggcta actggttggc tccccacatg gtgccctacg tctatatcac accttaaaga agctgaagag aagatgttaa aatgtgtgcc ttgcacatac aaaaaagaac ctgttcgtat atctaatgga aataaaatat ggacactgaa gttctctcat aatatttcaa ataagactcc acttgtcctt ctccatggtt ttggaggagg tcttgggctc tgggcactga attttggaga tctttgcacc aacagacctg tctatgcttt tgacctattg ggttttggac gaagtagtag acccaggttt gacagtgatg cagaagaagt ggagaatcag tttgtggaat ccattgaaga gtggagatgt gccctaggat tggacaaaat gatcttgctt gggcacaacc taggtggatt cttggctgct gcttactcgc tgaagtaccc atcaagggtt aatcatctca ttttagtgga gccttggggt ttccctgaac gaccagacct tgctgatcaa gacagaccaa ttccagtttg gatcagagcc ttgggagcag cattgactcc ctttaaccct ttagctggcc taaggattgc aggacccttt ggtttaagtc tagtgcagcg tttaaggcct gatttcaaac gaaagtattc ttcaatgttc gaagacgata ctgtgacaga atacatctac cactgtaatg tgcagactcc aagtggtgag acagctttca agaatatgac tattccttat ggatgggcaa aaaggccaat gctccagcga attggtaaaa tgcaccctga cattccagtt tcagtgatct ttggcgcccg atcctgcata gatggcaatt ctggcaccag catccagtcc ttacgaccac attcatatgt gaagacaata gctattcttg gggcaggaca ttatgtatat gcagatcaac cagaagaatt caaccagaaa gtaaaggaga tctgcgacac tgtggactga
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ABHD5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABHD5. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,096 Da
NCBI Official Full Name
Homo sapiens abhydrolase domain containing 5, mRNA
NCBI Official Synonym Full Names
abhydrolase domain containing 5
NCBI Official Symbol
ABHD5  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
1-acylglycerol-3-phosphate O-acyltransferase ABHD5
UniProt Protein Name
1-acylglycerol-3-phosphate O-acyltransferase ABHD5
UniProt Synonym Protein Names
Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58
UniProt Gene Name
ABHD5  [Similar Products]
UniProt Synonym Gene Names
NCIE2  [Similar Products]
UniProt Entry Name
NCBI Summary for ABHD5
The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]
UniProt Comments for ABHD5
ABHD5: a lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Colocalized with PLIN and ADFP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA. Defects cause neutral lipid storage disease (NLSD), an autosomal recessive disorder characterized by the excessive accumulation of neutral lipids in multiple tissues, and Chanarin-Dorfman syndrome (CDS), a triglyceride storage disease with impaired long-chain fatty acid oxidation and icthyosis. CDS is an autosomal recessive inborn error of lipid metabolism with multisystemic accumulation of triglycerides although plasma concentrations are normal. Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons.

Protein type: Transferase; Lipase; EC

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; lipid particle; nucleus

Molecular Function: lysophosphatidic acid acyltransferase activity; triacylglycerol lipase activity

Biological Process: phosphatidic acid biosynthetic process

Disease: Chanarin-dorfman Syndrome
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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