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ABI1 blocking peptide

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Catalog # MBS823342
Unit / Price
  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
ABI1 blocking peptide
Product Name

ABI1, Blocking Peptide

Also Known As

ABI1 Blocking Peptide

Product Synonym Names
SSH3BP1; Abl interactor 1; Abelson interactor 1; Abi-1; Abl-binding protein 4; AblBP4; Eps8 SH3 domain-binding protein; Eps8-binding protein; Nap1-binding protein; Nap1BP; Spectrin SH3 domain-binding protein 1; e3B1
Antibody/Peptide Pairs
ABI1 peptide (MBS823342) is used for blocking the activity of ABI1 antibody (MBS821351)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
481
3D Structure
ModBase 3D Structure for Q8IZP0
Host
Synthetic
Species Reactivity
Human, Mouse, Rat, Bovine
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of ABI1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABI1 blocking peptide
The peptide is used to block Anti-ABI1 Antibody reactivity.
Applications Tested/Suitable for ABI1 blocking peptide
Blocking (BL)
Application Notes for ABI1 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for ABI1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,548 Da
NCBI Official Full Name
abl interactor 1 isoform b
NCBI Official Synonym Full Names
abl-interactor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1
  [Similar Products]
NCBI Protein Information
abl interactor 1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding protein; spectrin SH3 domain-binding protein 1
UniProt Protein Name
Abl interactor 1
UniProt Synonym Protein Names
Abelson interactor 1; Abi-1; Ablphilin-1; Eps8 SH3 domain-binding protein; Eps8-binding protein; Spectrin SH3 domain-binding protein 1; e3B1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Ssh3bp1; Abi-1; Eps8-binding protein  [Similar Products]
UniProt Entry Name
ABI1_MOUSE
NCBI Summary for ABI1
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
UniProt Comments for ABI1
Abi-1: an SH3-containing adapter protein that regulates c-Abl-mediated phosphorylation of Mena. Binds the SH3 domains of epidermal growth factor receptor kinase substrate (EPS8) and of spectrin. May play a role in fusion of macropinocytic vesicles. Associated with congenital acute monocytic leukemia.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Cellular Component: neuron projection; leading edge; postsynaptic membrane; cytoskeleton; cell projection; membrane; lamellipodium; cytoplasm; plasma membrane; synapse; intracellular; cell junction; nucleus; filopodium

Molecular Function: protein binding; protein complex binding; protein tyrosine kinase activator activity

Biological Process: somitogenesis; peptidyl-tyrosine phosphorylation; cell motility; cellular process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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