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ABI2 cdna clone

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Catalog # MBS1274929
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ABI2 cdna clone
Product Name

ABI2, cDNA Clone

Also Known As

ABI2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1428
Sequence
atggcggagc tgcagatgct gctggaagag gaaatcccgg ggggccgccg ggccctcttc gacagctaca caaatctgga acgggtggcc gattactgcg agaacaacta catacagtca gcagataagc agagagccct agaagaaacc aaagcctaca ccacccaatc cttagcaagt gttgcctatc tgataaacac cttggccaac aatgtcctgc agatgctgga tatccaggca tcccagctac gaaggatgga atcttcaatc aatcatattt cacaaacagt tgatattcat aaagagaaag ttgcaagaag agaaattggt attttgacta ccaataaaaa cacttcaagg acacataaga ttattgctcc agccaacctt gaacgaccag ttcgttatat tagaaaacct attgactata caattctaga tgatattgga catggagtaa aggtgagtac ccagaacatg aagatgggtg ggctgccgcg tacaacacct ccaactcaga agccccctag tccccctatg tcagggaaag ggacacttgg gcggcactcc ccctatcgca cactggagcc agtgcgtcct ccagtggtac caaatgatta cgtacctagc ccaacccgta atatggctcc ctcgcagcag agccctgtga ggacagcttc tgtgaatcaa agaaatcgaa cttacagcag cagtgggagt agtggaggga gccacccaag tagtcggagc agcagtcgag agaacagtgg aagtggtagt gtgggggttc ctattgctgt tcctactcca tctcctccca gtgtctttcc aggtcatcct gtacagttct acagcatgaa taggcctgcc tctcgccata ctcccccaac aatagggggc tcgttgccct atagacgccc tccttccatt acttcacaaa caagccttca gaatcagatg aatggaggac ctttttatag ccagaatcca gtatctcttg ctcctcctcc tccctccatc ctacaggtaa ctcctcagtt acctttaatg ggatttgtgg ccagagtcca agaaaatatt tcagatacac cacctccacc gccacctgtg gaagaaccag tctttgatga gtctccccca cctcctcctc ctccagaaga ttacgaagag gaggaagctg ctgtggttga gtatagtgat ccttatgctg aagaggaccc accgtgggct ccacgttctt acttggaaaa ggttgtggca atttatgact atacaaaaga caaggaagat gagctgtcct ttcaggaagg agccattatt tatgtcatca agaagaatga cgatggttgg tatgagggag ttatgaatgg agtgactggg ctttttcctg ggaattacgt tgagtctatc atgcattatt ctgagtaa
OMIM
606442
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ABI2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ABI2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,819 Da
NCBI Official Full Name
Homo sapiens abl interactor 2, mRNA
NCBI Official Synonym Full Names
abl interactor 2
NCBI Official Symbol
NCBI Official Synonym Symbols
ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB
  [Similar Products]
NCBI Protein Information
abl interactor 2
UniProt Protein Name
Abl interactor 2
UniProt Synonym Protein Names
Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
ARGBPIA; Abi-2; AblBP3; ArgBP1  [Similar Products]
UniProt Entry Name
ABI2_HUMAN
UniProt Comments for ABI2
Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoplasm; cytosol; filopodium; lamellipodium

Molecular Function: cytoskeletal adaptor activity; DNA binding; protein binding; protein complex binding; Rac GTPase binding; SH3 domain binding; ubiquitin protein ligase binding

Biological Process: cell migration; cell motility; cytoskeleton organization and biogenesis; peptidyl-tyrosine phosphorylation; Rac protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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