BC011858
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,428 Da
NCBI Official Full Name
Homo sapiens ankyrin repeat and BTB (POZ) domain containing 1, mRNA
NCBI Official Synonym Full Names
ankyrin repeat and BTB domain containing 1
NCBI Official Synonym Symbols
BPOZ; BTB3; BTBD21; EF1ABP; PP2259 [Similar Products]
NCBI Protein Information
ankyrin repeat and BTB/POZ domain-containing protein 1
UniProt Protein Name
Ankyrin repeat and BTB/POZ domain-containing protein 1
UniProt Synonym Protein Names
Elongation factor 1A-binding protein
UniProt Entry Name
ABTB1_HUMAN
NCBI Summary for ABTB1
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for ABTB1
ABTB1: May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 3q21
Cellular Component: cytoplasm; nucleolus; plasma membrane; SCF ubiquitin ligase complex
Molecular Function: protein binding; ubiquitin protein ligase binding
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of proteolysis
Research Articles on ABTB1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with ABTB1 cdna clone
Organs/Tissues associated with ABTB1 cdna clone
|