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ACACA blocking peptide

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Catalog # MBS9222308
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
ACACA blocking peptide
Product Name

ACACA, Blocking Peptide

Also Known As

ACACA Antibody (C-term) Blocking Peptide

Product Synonym Names
Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Biotin carboxylase; ACACA; ACAC; ACC1; ACCA
Product Synonym Gene Name
ACAC; ACC1; ACCA[Similar Products]
Antibody/Peptide Pairs
ACACA peptide (MBS9222308) is used for blocking the activity of ACACA antibody (MBS9209560)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
2346
OMIM
200350
3D Structure
ModBase 3D Structure for Q13085
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasm.
Tissue Location
Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ACACA blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ACACA blocking peptide
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
NCBI/Uniprot data below describe general gene information for ACACA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
269,999 Da
NCBI Official Full Name
Acetyl-CoA carboxylase 1
NCBI Official Synonym Full Names
acetyl-CoA carboxylase alpha
NCBI Official Symbol
ACACA  [Similar Products]
NCBI Official Synonym Symbols
ACC; ACAC; ACC1; ACCA; ACACAD
  [Similar Products]
NCBI Protein Information
acetyl-CoA carboxylase 1
UniProt Protein Name
Acetyl-CoA carboxylase 1
UniProt Synonym Protein Names
ACC-alphaIncluding the following 1 domains:Biotin carboxylase (EC:6.3.4.14
UniProt Gene Name
ACACA  [Similar Products]
UniProt Synonym Gene Names
ACAC; ACC1; ACCA; ACC1  [Similar Products]
UniProt Entry Name
ACACA_HUMAN
NCBI Summary for ACACA
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ACACA
ACC1: a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC. ACC-alpha is the predominant isoform in liver, adipocyte and mammary gland. ACC-beta is the major isoform in skeletal muscle and heart. Phosphorylation regulates its activity.

Protein type: Carbohydrate Metabolism - pyruvate; EC 6.3.4.14; EC 6.4.1.2; Lipid Metabolism - fatty acid biosynthesis; Carbohydrate Metabolism - propanoate; Ligase

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: actin cytoskeleton; cytoplasm; cytosol; nucleolus

Molecular Function: acetyl-CoA carboxylase activity; protein binding

Biological Process: acetyl-CoA metabolic process; biotin metabolic process; carnitine shuttle; fatty acid biosynthetic process; positive regulation of cellular metabolic process; protein homotetramerization

Disease: Acetyl-coa Carboxylase Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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