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ACACB peptide

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Catalog # MBS425499
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
ACACB peptide
Product Name

ACACB, Peptide

Also Known As

ACACB Immunizing Peptide

Product Synonym Names
ACACB; acetyl-Coenzyme A carboxylase beta; ACCB; HACC275; acetyl-CoA carboxylase 2
Product Gene Name
Antibody/Peptide Pairs
ACACB peptide (MBS425499) is used for blocking the activity of ACACB antibody (MBS421052)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
2458
Sequence
C-QLGEPDLS DKDRKD
OMIM
601557
Species Reactivity
Human
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of ACACB peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACACB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
255,093 Da
NCBI Official Full Name
acetyl-Coenzyme A carboxylase beta
NCBI Official Synonym Full Names
acetyl-CoA carboxylase beta
NCBI Official Symbol
ACACB  [Similar Products]
NCBI Official Synonym Symbols
ACC2; ACCB; HACC275
  [Similar Products]
NCBI Protein Information
acetyl-CoA carboxylase 2
UniProt Protein Name
Acetyl-CoA carboxylase 2
UniProt Synonym Protein Names
ACC-betaIncluding the following 1 domains:Biotin carboxylase (EC:6.3.4.14)
UniProt Gene Name
ACACB  [Similar Products]
UniProt Synonym Gene Names
ACC2; ACCB  [Similar Products]
UniProt Entry Name
ACACB_HUMAN
NCBI Summary for ACACB
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for ACACB
ACC2: a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Activity is increased by oligomerization. Activated by citrate. Citrate and MID1IP1 promote oligomerization. Inhibited by malonyl-CoA. ACC1 is the predominant form expressed in liver, adipocyte and mammary gland. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC. ACC2 is the major isoform in skeletal muscle and heart. Phosphorylation regulates its activity. Two isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.4.1.2; Carbohydrate Metabolism - pyruvate; Mitochondrial; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid biosynthesis; EC 6.3.4.14; Ligase

Chromosomal Location of Human Ortholog: 12q24.11

Cellular Component: cytosol; endomembrane system; mitochondrial outer membrane; mitochondrion; nucleus

Molecular Function: acetyl-CoA carboxylase activity; ATP binding; biotin carboxylase activity; metal ion binding; protein binding

Biological Process: acetyl-CoA metabolic process; biotin metabolic process; carnitine shuttle; fatty acid biosynthetic process; negative regulation of catalytic activity; negative regulation of fatty acid beta-oxidation; positive regulation of cellular metabolic process; protein homotetramerization; response to nutrient levels
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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