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ACOT8 recombinant protein :: Acyl-coenzyme A thioesterase 8 (ACOT8) Recombinant Protein

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Catalog # MBS1105373
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $725 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $830 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $975 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,060 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,070 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,125 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,270 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,300 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,530 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,620 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,000 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,020 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,115 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,095 +3 FREE 8GB USB
ACOT8 recombinant protein
Product Name

Acyl-coenzyme A thioesterase 8 (ACOT8), Recombinant Protein

Full Product Name

Recombinant Human Acyl-coenzyme A thioesterase 8 (ACOT8)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-319aa, Full length protein
Sequence
MSSPQAPEDG QGCGDRGDPP GDLRSVLVTT VLNLEPLDED LFRGRHYWVP AKRLFGGQIV GQALVAAAKS VSEDVHVHSL HCYFVRAGDP KLPVLYQVER TRTGSSFSVR SVKAVQHGKP IFICQASFQQ AQPSPMQHQF SMPTVPPPEE LLDCETLIDQ YLRDPNLQKR YPLALNRIAA QEVPIEIKPV NPSPLSQLQR MEPKQMFWVR ARGYIGEGDM KMHCCVAAYI SDYAFLGTAL LPHQWQHKVH FMVSLDHSMW FHAPFRADHW MLYECESPWA GGSRGLVHGR LWRQDGVLAV TCAQEGVIRV KPQVSESKL
OMIM
608123
3D Structure
ModBase 3D Structure for O14734
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ACOT8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ACOT8 recombinant protein
This protein is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for ACOT8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,914 Da
NCBI Official Full Name
acyl-coenzyme A thioesterase 8
NCBI Official Synonym Full Names
acyl-CoA thioesterase 8
NCBI Official Symbol
ACOT8  [Similar Products]
NCBI Official Synonym Symbols
hTE; NAP1; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III
  [Similar Products]
NCBI Protein Information
acyl-coenzyme A thioesterase 8
UniProt Protein Name
Acyl-coenzyme A thioesterase 8
UniProt Synonym Protein Names
Choloyl-coenzyme A thioesterase; HIV-Nef-associated acyl-CoA thioesterase; PTE-2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; PTE-1; Peroxisomal long-chain acyl-CoA thioesterase 1; Thioesterase II; hACTE-III; hACTEIII; hTE
UniProt Gene Name
ACOT8  [Similar Products]
UniProt Synonym Gene Names
ACTEIII; PTE1; PTE2; Acyl-CoA thioesterase 8; PTE-1; hACTE-III; hACTEIII; hTE  [Similar Products]
NCBI Summary for ACOT8
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010]
UniProt Comments for ACOT8
Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:9299485, PubMed:9153233, PubMed:15194431). Competes with bile acid CoA:amino acid N-acyltransferase (BAAT) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (C2 to C20) (PubMed:9299485, PubMed:9153233). Inactive towards substrates with more than C20 aliphatic chains (PubMed:9153233). Involved in the metabolic regulation of peroxisome proliferation (PubMed:15194431).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ACOT8 recombinant protein
 Reference Product  PubMed Publications
 ACOT4 recombinant protein  >2 publications with ACOT8 and ACOT4
Diseases associated with ACOT8 recombinant protein
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