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ACTL6A peptide :: BAF53A and BAF53B Peptide

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Catalog # MBS425661
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
ACTL6A peptide
Product Name

BAF53A and BAF53B (ACTL6A), Peptide

Also Known As

BAF53A and BAF53B Immunizing Peptide

Product Synonym Names
BAF53A; BAF53B; ACTL6; BAF53a; BAF53b; actin-like 6A; actin-like 6B; hArpN alpha; actin-related protein; ACTL6A; ACTL6B; 53 kDa BRG1-associated factor B; ARPN-BETA; MGC5382 Arp4; INO80K; BAF complex 53 kDa subunit; BAF53; BRG1-associated factor; INO80 com; BAF53A and BAF53B
Product Gene Name
Product Synonym Gene Name
BAF53A; BAF53B[Similar Products]
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
429
Sequence
YEEGGKQCVE RKCP
OMIM
604958
Species Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of ACTL6A peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACTL6A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_817126.1; NP_057272.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,236 Da
NCBI Official Full Name
actin-like protein 6A isoform 1
NCBI Official Synonym Full Names
actin like 6A
NCBI Official Symbol
ACTL6A  [Similar Products]
NCBI Official Synonym Symbols
Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA
  [Similar Products]
NCBI Protein Information
actin-like protein 6A
UniProt Protein Name
Actin-like protein 6A
UniProt Synonym Protein Names
53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K
Protein Family
UniProt Gene Name
ACTL6A  [Similar Products]
UniProt Synonym Gene Names
BAF53; BAF53A; INO80K; BAF53A  [Similar Products]
UniProt Entry Name
ACL6A_HUMAN
NCBI Summary for ACTL6A
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for ACTL6A
BAF53A: an actin-related protein involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of the helicase SMARCA4 and for association of the SMARCA4 containing remodelling complex BAF with chromatin/nuclear matrix. A component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of specific genes. Two alternatively spliced human isoforms have been described.

Chromosomal Location of Human Ortholog: 3q26.33

Cellular Component: NuA4 histone acetyltransferase complex; nuclear chromatin; nucleoplasm; nucleus; plasma membrane; protein complex; SWI/SNF complex

Molecular Function: chromatin binding; nucleosomal DNA binding; protein binding; transcription coactivator activity

Biological Process: ATP-dependent chromatin remodeling; chromatin remodeling; DNA recombination; DNA repair; regulation of growth; regulation of transcription from RNA polymerase II promoter; signal transduction; spinal cord development; transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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