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ACVR1 recombinant protein :: Activin receptor type-1 (ACVR1) Recombinant Protein

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Catalog # MBS1407651
Unit / Price
Scan QR to view Datasheet
  0.5 mg (E-Coli)  /  $835 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $835 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,060 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,060 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,200 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,200 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,655 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,655 +2 FREE 8GB USB
ACVR1 recombinant protein
Product Name

Activin receptor type-1 (ACVR1), Recombinant Protein

Full Product Name

Recombinant Chicken Activin receptor type-1 (ACVR1), partial

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
17-119
Sequence
VQDE ELKLNECVCE GMSCGNGDRC QGQQCFASLS INDGAKVYQK GCFQVYEQGK MTCKTPPSPD QAVECCQGYL CNMNITAKLP SSKGQTLQGE AAGYSMETL
3D Structure
ModBase 3D Structure for Q90ZK6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Chicken
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ACVR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ACVR1 recombinant protein
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine
threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
NCBI/Uniprot data below describe general gene information for ACVR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,225 Da
NCBI Official Full Name
activin receptor type-1
NCBI Official Synonym Full Names
activin A receptor type 1
NCBI Official Symbol
ACVR1  [Similar Products]
NCBI Official Synonym Symbols
ALK2; ATVR1
  [Similar Products]
NCBI Protein Information
activin receptor type-1
UniProt Protein Name
Activin receptor type-1
UniProt Synonym Protein Names
Activin receptor type I; Type I TGF B receptor
Protein Family
UniProt Gene Name
ACVR1  [Similar Products]
UniProt Comments for ACVR1
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ACVR1 recombinant protein
 Reference Product  PubMed Publications
 SMAD3 recombinant protein  >5 publications with ACVR1 and SMAD3
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