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Adam12 recombinant protein :: Disintegrin and metalloproteinase domain-containing protein 12 (Adam12) Recombinant Protein

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Catalog # MBS1351735
Unit / Price
  0.01 mg (Baculovirus)  /  $235 +1 FREE 8GB USB
  0.01 mg (E-Coli)  /  $235 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $320 +1 FREE 8GB USB
  0.02 mg (Baculovirus)  /  $355 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $535 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $680 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $855 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $940 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,325 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $1,845 +2 FREE 8GB USB
SDS-Page
Product Name

Disintegrin and metalloproteinase domain-containing protein 12 (Adam12), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse Disintegrin and metalloproteinase domain-containing protein 12 (Adam12), partial

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
206-706. Partial. The complete extracellular domain.
Sequence
ETLKMTKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH VDKFYRPLNI RIVLVGVEVW NDIDKCSISQ DPFTSLHEFL DWRKIKLLPR KSHDNAQLIS GVYFQGTTIG MAPIMSMCTA EQSGGVVMDH SDSPLGAAVT LAHELGHNFG MNHDTLERGC SCRMAAEKGG CIMNPSTGFP FPMVFSSCSR KDLEASLEKG MGMCLFNLPE VKQAFGGRKC GNGYVEEGEE CDCGEPEECT NRCCNATTCT LKPDAVCAHG QCCEDCQLKP PGTACRGSSN SCDLPEFCTG TAPHCPANVY LHDGHPCQGV DGYCYNGICQ THEQQCVTLW GPGAKPAPGI CFERVNSAGD PYGNCGKDSK SAFAKCELRD AKCGKIQCQG GASRPVIGTN AVSIETNIPQ QEGGRILCRG THVYLGDDMP DPGLVLAGTK CAEGKICLNR RCQNISVFGV HKCAMQCHGR GVCNNRKNCH CEAHWAPPFC DKFGFGGSTD SGPIRQADNQ G
3D Structure
ModBase 3D Structure for Q61824
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Adam12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Adam12 recombinant protein
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

Adam12 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Adam12. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
98,504 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 12 preproprotein
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
NCBI Official Symbol
Adam12  [Similar Products]
NCBI Official Synonym Symbols
Mltna
  [Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 12
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 12
UniProt Synonym Protein Names
Meltrin-alpha
UniProt Gene Name
Adam12  [Similar Products]
UniProt Synonym Gene Names
Mltna; ADAM 12  [Similar Products]
NCBI Summary for Adam12
This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein that localizes to the cell surface. About a third of the mice lacking the encoded protein die before weaning. Overexpression of the encoded protein in a mouse model of Duchenne muscular dystrophy alleviates the muscle pathology by preventing cell necrosis and inflammation. [provided by RefSeq, May 2016]
UniProt Comments for Adam12
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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