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ADAM5 recombinant protein :: A Disintegrin And Metalloprotease 5 (ADAM5) Recombinant Protein

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Catalog # MBS2010896 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $145 +1 FREE 8GB USB
  0.05 mg  /  $275 +1 FREE 8GB USB
  0.1 mg  /  $430 +1 FREE 8GB USB
  0.2 mg  /  $525 +1 FREE 8GB USB
  0.5 mg  /  $1,015 +1 FREE 8GB USB
  1 mg  /  $1,515 +1 FREE 8GB USB
SDS-Page
Product Name

A Disintegrin And Metalloprotease 5 (ADAM5), Recombinant Protein

Popular Item
Full Product Name

Recombinant A Disintegrin And Metalloprotease 5 (ADAM5)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-CDFEEY CN GNDAYCVPDT FARNGQYCDS GQAFCYSGLC MTSNNQCMNL LGKYVRGASF ACYEEFNSRN DRFGNCIRKF CSFENSLCGK LVCTWPFKRL LMKDNMSAAY GQIRDDLCIS LYKGGRPLKT TLSTYSDMSE RDETFVKDGT ICGPDMFCLE TQCKETRFLV DFQQCNTSRD CNDHGVCNNF NHCHCDKGYN PPYCESVKGQ FGSIDDGHKY YIDEGKSAKQ QNRGIHPKQ
Chromosome Location
Chromosome: 16; NC_005115.3 (71658527..71732482). Location: 16q12.4
3D Structure
ModBase 3D Structure for Q5BK84
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Organism
Rattus norvegicus (Rat)
Expression System
Prokaryotic expression
Residues
Cys413~Gln649 (Accession # Q5BK84) with N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of ADAM5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ADAM5 recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for ADAM5 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

NCBI/Uniprot data below describe general gene information for ADAM5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
28.4kDa
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 5
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 5
NCBI Official Symbol
Adam5  [Similar Products]
NCBI Official Synonym Symbols
tMDCII
  [Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 5; tMDC II; ADAM metallopeptidase domain 5; a disintegrin and metalloprotease domain 5; a disintegrin and metalloprotease domain (ADAM) 5; transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 5
UniProt Synonym Protein Names
Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II
UniProt Gene Name
Adam5  [Similar Products]
UniProt Synonym Gene Names
Tmdc2; tMDC II  [Similar Products]
UniProt Entry Name
ADAM5_RAT
NCBI Summary for ADAM5
germ-cell specific metalloprotease-disintegrin that may play a role in cell-cell and cell-matrix interactions during spermatogenesis [RGD, Feb 2006]
UniProt Comments for ADAM5
ADAM5P: This is a non catalytic metalloprotease-like protein. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease

Cellular Component: integral to membrane

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with ADAM5 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >9 publications with ADAM5 and Testis
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