NP_031428.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
89,188 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 7 preproprotein
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 7
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 7
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 7
UniProt Synonym Gene Names
UniProt Entry Name
ADAM7_MOUSE
NCBI Summary for Adam7
This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is specifically expressed in epididymis where the encoded protein is transferred to the sperm surface during epididymal transit. This gene is located adjacent to a related gene from the ADAM family of proteins on chromosome 14. [provided by RefSeq, Oct 2015]
UniProt Comments for Adam7
ADAM7: May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Protease
Cellular Component: apical part of cell; plasma membrane
Molecular Function: endopeptidase activity
Research Articles on Adam7
Precautions
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Products associated with Adam7 recombinant protein
Diseases associated with Adam7 recombinant protein
Organs/Tissues associated with Adam7 recombinant protein
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