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ADAMTS7 recombinant protein :: A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Recombinant Protein

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Catalog # MBS2010788 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $135 +1 FREE 8GB USB
  0.05 mg  /  $250 +1 FREE 8GB USB
  0.1 mg  /  $385 +1 FREE 8GB USB
  0.2 mg  /  $470 +1 FREE 8GB USB
  0.5 mg  /  $910 +1 FREE 8GB USB
  1 mg  /  $1,345 +1 FREE 8GB USB
Product Name

A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7), Recombinant Protein

Popular Item
Also Known As

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1686
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-VQ RRLVKCVNTQ TGLPEEDSDQ CGHEAWPESS RPCGTEDCEP VEPPRCERDR LSFGFCETLR LLGRCQLPTI RTQCCRSCSP PSHGAPSRGH QRVARR
Chromosome Location
Chromosome: 15; NC_000015.9 (79051545..79103805, complement). Location: 15q24.2
OMIM
605009
3D Structure
ModBase 3D Structure for Q9UKP4
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.
Residues
Val1589~Arg1686
Tags Information
N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug(determined by the LAL method).
Predicted isoelectric point
7.6
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of ADAMTS7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for ADAMTS7 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Sequence Information of ADAMTS7 recombinant protein
ADAMTS7 recombinant protein Sequence Information image
NCBI/Uniprot data below describe general gene information for ADAMTS7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12.6kDa
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif, 7
NCBI Official Symbol
ADAMTS7  [Similar Products]
NCBI Official Synonym Symbols
ADAM-TS7; ADAMTS-7; ADAM-TS 7
  [Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 7
UniProt Synonym Protein Names
COMPase
UniProt Gene Name
ADAMTS7  [Similar Products]
UniProt Synonym Gene Names
ADAM-TS 7; ADAM-TS7; ADAMTS-7  [Similar Products]
UniProt Entry Name
ATS7_HUMAN
NCBI Summary for ADAMTS7
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]
UniProt Comments for ADAMTS7
ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.

Protein type: Cell surface; Secreted, signal peptide; Secreted; EC 3.4.24.-; Protease; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen

Molecular Function: protein binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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