NP_891550.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
213,420 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 9
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 9
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 9
UniProt Synonym Gene Names
NCBI Summary for ADAMTS9
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
UniProt Comments for ADAMTS9
Cleaves the large aggregating proteoglycans, aggrecan (at the '1838-Glu-|-Ala-1839' site) and versican (at the '1428-Glu-|-Ala-1429' site). Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos.
Research Articles on ADAMTS9
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Products associated with ADAMTS9 elisa kit
Pathways associated with ADAMTS9 elisa kit
Diseases associated with ADAMTS9 elisa kit
Organs/Tissues associated with ADAMTS9 elisa kit
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