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ADCY1 clia kit :: Human ADCY1 (Adenylate Cyclase 1, Brain) CLIA Kit

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Catalog # MBS2531245
Unit / Price
  48-Strip-Wells  /  $450 +1 FREE 8GB USB
  96-Strip-Wells  /  $535 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
  10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

ADCY1 (Adenylate Cyclase 1, Brain), CLIA Kit

Also Known As

Human ADCY1 (Adenylate Cyclase 1, Brain) CLIA Kit

Product Synonym Names
AC1
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Sequence Length
1119
OMIM
103072
3D Structure
ModBase 3D Structure for Q08828
Species Reactivity
Specificity
This kit recognizes natural and recombinant ADCY1. No significant cross-reactivity or interference between ADCY1 and analogues was observed.
Assay Type
Sandwich
Detection Range
0.156-10ng/mL
Sensitivity
Min: 0.094ng/mL; Max: 10ng/mL
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ADCY1 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ADCY1 clia kit
Intended Uses: This CLIA kit applies to the in vitro quantitative determination of ADCY1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to ADCY1. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ADCY1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ADCY1, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of ADCY1. You can calculate the concentration of ADCY1 in the samples by comparing the RLU value of the samples to the standard curve.

Typical Testing Data/Standard Curve (for reference only) of ADCY1 clia kit
ADCY1 clia kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS2531245. Click to request current manual
NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,440 Da
NCBI Official Full Name
adenylate cyclase type 1 isoform 1
NCBI Official Synonym Full Names
adenylate cyclase 1
NCBI Official Symbol
ADCY1  [Similar Products]
NCBI Official Synonym Symbols
AC1; DFNB44
  [Similar Products]
NCBI Protein Information
adenylate cyclase type 1
UniProt Protein Name
Adenylate cyclase type 1
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
Protein Family
UniProt Gene Name
ADCY1  [Similar Products]
UniProt Entry Name
ADCY1_HUMAN
NCBI Summary for ADCY1
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ADCY1
ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Transporter; Adenylyl cyclase; Transporter, aquaporin family; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Membrane protein, integral; Lyase; EC 4.6.1.1

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; circadian rhythm; response to drug; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; response to lithium ion; activation of protein kinase A; regulation of circadian rhythm; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; cAMP-mediated signaling; axonogenesis; long-term memory; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport

Disease: Deafness, Autosomal Recessive 44
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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