NP_066939.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,440 Da
NCBI Official Full Name
adenylate cyclase type 1 isoform 1
NCBI Official Synonym Full Names
adenylate cyclase 1
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 1
UniProt Protein Name
Adenylate cyclase type 1
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
UniProt Entry Name
ADCY1_HUMAN
NCBI Summary for ADCY1
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ADCY1
ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.
Protein type: Transporter; Adenylyl cyclase; Transporter, aquaporin family; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Membrane protein, integral; Lyase; EC 4.6.1.1
Chromosomal Location of Human Ortholog: 7p12.3
Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus
Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding; adenylate cyclase activity
Biological Process: epidermal growth factor receptor signaling pathway; circadian rhythm; response to drug; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; response to lithium ion; activation of protein kinase A; regulation of circadian rhythm; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; cAMP-mediated signaling; axonogenesis; long-term memory; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
Disease: Deafness, Autosomal Recessive 44
Research Articles on ADCY1
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Pathways associated with ADCY1 clia kit
Organs/Tissues associated with ADCY1 clia kit
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