NP_001161221.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
169,750 Da
NCBI Official Full Name
adenylate cyclase type 10 isoform 2
NCBI Official Synonym Full Names
adenylate cyclase 10
NCBI Official Synonym Symbols
SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a [Similar Products]
NCBI Protein Information
adenylate cyclase type 10
UniProt Protein Name
Adenylate cyclase type 10
UniProt Synonym Protein Names
AH-related protein; Adenylate cyclase homolog; Germ cell soluble adenylyl cyclase
UniProt Synonym Gene Names
NCBI Summary for ADCY10
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]
UniProt Comments for ADCY10
Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO2 levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (). Involved in ciliary beat regulation (PubMed:17591988).
Research Articles on ADCY10
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Products associated with ADCY10 elisa kit
Pathways associated with ADCY10 elisa kit
Diseases associated with ADCY10 elisa kit
Organs/Tissues associated with ADCY10 elisa kit
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