NP_066193.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
124,865 Da
NCBI Official Full Name
adenylate cyclase type 6 isoform b
NCBI Official Synonym Full Names
adenylate cyclase 6
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 6; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; adenylate cyclase type VI; ca(2+)-inhibitable adenylyl cyclase
UniProt Protein Name
Adenylate cyclase type 6
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase
UniProt Synonym Gene Names
UniProt Entry Name
ADCY6_HUMAN
NCBI Summary for ADCY6
This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for ADCY6
ADCY6: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Expressed in normal thyroid and brain tissues, as well as some tumors; its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.
Protein type: Transporter, aquaporin family; EC 4.6.1.1; Adenylyl cyclase; Lyase; Nucleotide Metabolism - purine; Transporter; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q12-q13
Cellular Component: membrane; integral to membrane; plasma membrane; cilium
Molecular Function: protein binding; metal ion binding; protein kinase binding; ATP binding; adenylate cyclase activity
Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; dopamine receptor signaling pathway; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; G-protein signaling, adenylate cyclase activating pathway; transmembrane transport
Disease: Lethal Congenital Contracture Syndrome 8
Research Articles on ADCY6
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Products associated with ADCY6 elisa kit
Pathways associated with ADCY6 elisa kit
Diseases associated with ADCY6 elisa kit
Organs/Tissues associated with ADCY6 elisa kit
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