NP_001121159.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,616 Da
NCBI Official Synonym Full Names
adiponectin receptor 1
NCBI Official Synonym Symbols
CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A [Similar Products]
NCBI Protein Information
adiponectin receptor protein 1
UniProt Protein Name
Adiponectin receptor protein 1
UniProt Synonym Protein Names
Progestin and adipoQ receptor family member I
UniProt Synonym Gene Names
UniProt Entry Name
ADR1_HUMAN
NCBI Summary for ADIPOR1
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
UniProt Comments for ADIPOR1
ADIPOR1: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. Belongs to the ADIPOR family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: adiponectin binding; identical protein binding; hormone binding; protein heterodimerization activity; receptor activity; protein kinase binding
Biological Process: hormone-mediated signaling; positive regulation of JAK-STAT cascade; adiponectin-mediated signaling pathway; fatty acid oxidation; negative regulation of cell growth; positive regulation of insulin receptor signaling pathway; leptin-mediated signaling pathway
Research Articles on ADIPOR1
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Pathways associated with ADIPOR1 elisa kit
Diseases associated with ADIPOR1 elisa kit
Organs/Tissues associated with ADIPOR1 elisa kit
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