NP_006712
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
adenosine kinase isoform b
NCBI Official Synonym Full Names
adenosine kinase
NCBI Official Synonym Symbols
NCBI Protein Information
adenosine kinase
UniProt Protein Name
Adenosine kinase
UniProt Synonym Protein Names
Adenosine 5'-phosphotransferase
UniProt Synonym Gene Names
NCBI Summary for ADK
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
UniProt Comments for ADK
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Product References and Citations for ADK active protein
Chakraborty, A., et al. (2002) J. Biol. Chem. 277:47451-47451.; Sakowicz M., et al. (2001) Acta Biochim Pol. 48 (3):745-54.
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Products associated with ADK active protein
Pathways associated with ADK active protein
Diseases associated with ADK active protein
Organs/Tissues associated with ADK active protein
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