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AGA recombinant protein

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Catalog # MBS206447
Unit / Price
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  0.01 mg  /  $310 +1 FREE 8GB USB
  0.05 mg  /  $925 +1 FREE 8GB USB
SDS-Page
Product Name

AGA, Recombinant Protein

Full Product Name

AGA, 24-346aa, Human, His-tag, Baculovirus

Product Synonym Names
N (4)- (beta-N-acetylglucosaminyl)-L-asparaginase isoform 1; AGA; AGU; ASRG; GA
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ADPSSPLPLV VNTWPFKNAT EAAWRALASG GSALDAVESG CAMCEREQCD GSVGFGGSPD ELGETTLDAM IMDGTTMDVG AVGDLRRIKN AIGVARKVLE HTTHTLLVGE SATTFAQSMG FINEDLSTTA SQALHSDWLA RNCQPNYWRN VIPDPSKYCG PYKPPGILKQ DIPIHKETED DRGHDTIGMV VIHKTGHIAA GTSTNGIKFK IHGRVGDSPI PGAGAYADDT AGAAAATGNG DILMRFLPSY QAVEYMRRGE DPTIACQKVI SRIQKHFPEF FGAVICANVT GSYGAACNKL STFTQFSFMV YNSEKNQPTE EKVDCIHHHH HH
OMIM
X55762 mRNA
3D Structure
ModBase 3D Structure for P20933
Host
Baculovirus
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration
0.25mg/ml (determined by Absorbance at 280nm) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of AGA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AGA recombinant protein
AGA, as known as N (4)- (beta-N-acetylglucosaminyl)-L-asparaginase isoform 1, belongs to the N-terminal nucleophile (Ntn) hydrolase superfamily. This protein consists of different S100 proteins and then plays various roles in regulation of protein phosphorylation, the dynamics of cytoskeleton constituents, transcription factors, enzyme activities, cell growth and differentiation, and inflammatory response. Recombinant human AGA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for AGA recombinant protein
Applications Tested/Suitable for AGA recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for AGA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35.7kDa (332aa) 18-57kDa (SDS-PAGE under reducing conditions.)
NCBI Official Full Name
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase isoform 1 preproprotein
NCBI Official Synonym Full Names
aspartylglucosaminidase
NCBI Official Symbol
NCBI Official Synonym Symbols
GA; AGU; ASRG
  [Similar Products]
NCBI Protein Information
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
UniProt Protein Name
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
UniProt Synonym Protein Names
Aspartylglucosaminidase; Glycosylasparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase
Protein Family
UniProt Gene Name
NCBI Summary for AGA
This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. [provided by RefSeq, Nov 2015]
UniProt Comments for AGA
Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
Product References and Citations for AGA recombinant protein
Saarela J., et al. (2004) Biochem. J. 378:363-371.; Ikonen E., et al. (1992) Hum. Mutat. 1:361-365.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with AGA recombinant protein
 Reference Product  PubMed Publications
 GAA recombinant protein  >34 publications with AGA and GAA
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