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AGPAT1 recombinant protein :: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1) Recombinant Protein

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Catalog # MBS7007387
Unit / Price
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  0.01 mg  /  $915 +1 FREE 8GB USB
  0.05 mg  /  $1,415 +1 FREE 8GB USB
  0.1 mg  /  $2,340 +2 FREE 8GB USB
AGPAT1 recombinant protein
Product Name

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1), Recombinant Protein

Full Product Name

Recombinant Human 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-283aa; full length protein
Sequence
FCSPSAKYFF KMAFYNGWIL FLAVLAIPVC AVRGRNVENM KILRLMLLHI KYLYGIRVEV RGAHHFPPSQ PYVVVSNHQS SLDLLGMMEV LPGRCVPIAK RELLWAGSAG LACWLAGVIF IDRKRTGDAI SVMSEVAQTL LTQDVRVWVF PEGTRNHNGS MLPFKRGAFH LAVQAQVPIV PIVMSSYQDF YCKKERRFTS GQCQVRVLPP VPTEGLTPDD VPALADRVRH SMLTVFREIS TDGRGGGDYL KKPGGGG
OMIM
603099
3D Structure
ModBase 3D Structure for Q99943
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AGPAT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for AGPAT1 recombinant protein
Application Notes for AGPAT1 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for AGPAT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,717 Da
NCBI Official Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 1
NCBI Official Symbol
AGPAT1  [Similar Products]
NCBI Official Synonym Symbols
G15; LPAATA; 1-AGPAT1; LPAAT-alpha
  [Similar Products]
NCBI Protein Information
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
UniProt Protein Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15
UniProt Gene Name
AGPAT1  [Similar Products]
UniProt Synonym Gene Names
G15; 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha  [Similar Products]
UniProt Entry Name
PLCA_HUMAN
NCBI Summary for AGPAT1
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for AGPAT1
AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Transferase; Membrane protein, integral; Membrane protein, multi-pass; Lipid Metabolism - ether lipid; EC 2.3.1.51

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; protein binding

Biological Process: CDP-diacylglycerol biosynthetic process; phosphatidic acid biosynthetic process; phospholipid metabolic process; positive regulation of cellular metabolic process; positive regulation of cytokine and chemokine mediated signaling pathway; positive regulation of cytokine production; triacylglycerol biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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