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Agpat2 recombinant protein :: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (Agpat2) Recombinant Protein

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Catalog # MBS7007391
Unit / Price
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  0.01 mg  /  $910 +1 FREE 8GB USB
  0.05 mg  /  $1,410 +1 FREE 8GB USB
  0.1 mg  /  $2,335 +2 FREE 8GB USB
Agpat2 recombinant protein
Product Name

1-acyl-sn-glycerol-3-phosphate acyltransferase beta (Agpat2), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (Agpat2)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-278aa; full length protein
Sequence
MDPWPWLTAA LLLLLLLVQL SRTARFYAKV GLYCVLCLSF SAAASIVCLL RHGGRTVDNM SIISWFVRSF KYVYGLRFEV SGQKKLEVDG PCVIISNHQS ILDMMGLMEI LPKRCVQIAK RELMFTGPVG LIMYLGGVYF INRQQARTAM SVMADLGDLM VKENLKVWIY PEGTRNDNGD LLPFKKGAFY LAIQAQVPII PVVYSSFSSF YNVKTKLFTS GTIKVQVLDA VPTNGLTDAD VTKLVDTCYQ SMRATFLQIS QIPQENSAIK EPGVLPAQ
3D Structure
ModBase 3D Structure for Q8K3K7
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Agpat2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Agpat2 recombinant protein
Application Notes for Agpat2 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Agpat2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
31,011 Da
NCBI Official Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
NCBI Official Symbol
Agpat2  [Similar Products]
NCBI Official Synonym Symbols
BSCL; BSCL1; LPAAB; AV000834; LPAAT-beta; 2510002J07Rik
  [Similar Products]
NCBI Protein Information
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
UniProt Protein Name
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 2; 1-AGP acyltransferase 2; 1-AGPAT 2; Lysophosphatidic acid acyltransferase beta; LPAAT-beta
UniProt Gene Name
Agpat2  [Similar Products]
UniProt Synonym Gene Names
1-AGP acyltransferase 2; 1-AGPAT 2; LPAAT-beta  [Similar Products]
UniProt Entry Name
PLCB_MOUSE
UniProt Comments for Agpat2
AGPAT2: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Defects in AGPAT2 are the cause of congenital generalized lipodystrophy type 1 (CGL1); also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1) or Berardinelli-Seip syndrome. CGL1 is an autosomal recessive disorder characterized by marked paucity of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Lipid Metabolism - ether lipid; Transferase; EC 2.3.1.51; Lipid Metabolism - glycerolipid

Cellular Component: endoplasmic reticulum; integral to membrane; membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; transferase activity; transferase activity, transferring acyl groups

Biological Process: glycerophospholipid biosynthetic process; lipid metabolic process; metabolic process; phosphatidic acid biosynthetic process; phospholipid biosynthetic process; positive regulation of cytokine production
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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