NP_036243.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (AHSA1), mRNA
NCBI Official Synonym Full Names
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
NCBI Protein Information
activator of 90 kDa heat shock protein ATPase homolog 1
UniProt Protein Name
Activator of 90 kDa heat shock protein ATPase homolog 1
UniProt Synonym Protein Names
p38
UniProt Synonym Gene Names
UniProt Entry Name
AHSA1_HUMAN
UniProt Comments for AHSA1
Function: Cochaperone that stimulates HSP90 ATPase activity
By similarity. May affect a step in the endoplasmic reticulum to Golgi trafficking.
Subunit structure: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1. Interacts with SRPK1. Ref.8 Ref.9 Ref.10 Ref.11 Ref.12
Subcellular location: Cytoplasm › cytosol. Endoplasmic reticulum. Note: May transiently interact with the endoplasmic reticulum. Ref.8
Tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta. Ref.8
Induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG). Ref.9
Sequence similarities: Belongs to the AHA1 family.
Product References and Citations for AHSA1 recombinant protein
[1] "Isolation of a novel gene underexpressed in Down syndrome."
Research Articles on AHSA1
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Diseases associated with AHSA1 recombinant protein
Organs/Tissues associated with AHSA1 recombinant protein
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