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AIF1 cdna clone

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Catalog # MBS1273921
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
AIF1 cdna clone
Product Name

AIF1, cDNA Clone

Popular Item
Full Product Name

AIF1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgagccaaa ccagggattt acagggagga aaagctttcg gactgctgaa ggcccagcag gaagagaggc tggatgagat caacaagcaa ttcctagacg atcccaaata tagcagtgat gaggatctgc cctccaaact ggaaggcttc aaagagaaat acatggagtt tgaccttaat ggaaatggcg atattgatat catgtccctg aaacgaatgc tggagaaact tggagtcccc aagactcacc tagagctaaa gaaattaatt ggagaggtgt ccagtggctc cggggagacg ttcagctacc ctgactttct caggatgatg ctgggcaaga gatctgccat cctaaaaatg atcctgatgt atgaggaaaa agcgagagaa aaggaaaagc caacaggccc cccagccaag aaagctatct ctgagttgcc ctga
OMIM
601833
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AIF1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AIF1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,617 Da
NCBI Official Full Name
Homo sapiens allograft inflammatory factor 1, mRNA
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
IBA1; IRT1; AIF-1; IRT-1
  [Similar Products]
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
UniProt Synonym Protein Names
Ionized calcium-binding adapter molecule 1; Protein G1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
G1; IBA1; AIF-1  [Similar Products]
UniProt Entry Name
AIF1_HUMAN
NCBI Summary for AIF1
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
UniProt Comments for AIF1
AIF1: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: actin filament; cytoplasm; cytosol; lamellipodium; nucleus; perinuclear region of cytoplasm; phagocytic cup

Molecular Function: actin filament binding; calcium ion binding

Biological Process: actin filament bundle formation; actin filament polymerization; inflammatory response; negative regulation of smooth muscle cell proliferation; phagocytosis, engulfment; positive regulation of smooth muscle cell proliferation; positive regulation of T cell proliferation; Rac protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with AIF1 cdna clone
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