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AIP peptide :: AIP / ARA9 Peptide

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Catalog # MBS427008
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
AIP peptide
Product Name

AIP / ARA9, Peptide

Also Known As

AIP / ARA9 Immunizing Peptide

Product Synonym Names
AIP; ARA9; aryl hydrocarbon receptor interacting protein; FKBP16; FKBP37; XAP2; HBV-X associated protein; aryl hydrocarbon receptor-interacting protein; AIP / ARA9
Product Gene Name
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
330
Sequence
C-EARIRQKD EEDKAR
OMIM
102200
Species Reactivity
Human, Mouse, Rat, Dog
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of AIP peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AIP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,636 Da
NCBI Official Full Name
aryl hydrocarbon receptor interacting protein
NCBI Official Synonym Full Names
aryl hydrocarbon receptor interacting protein
NCBI Official Symbol
NCBI Official Synonym Symbols
ARA9; XAP2; XAP-2; FKBP16; FKBP37; SMTPHN
  [Similar Products]
NCBI Protein Information
AH receptor-interacting protein
UniProt Protein Name
AH receptor-interacting protein
UniProt Synonym Protein Names
Aryl-hydrocarbon receptor-interacting protein; HBV X-associated protein 2; XAP-2; Immunophilin homolog ARA9
UniProt Gene Name
UniProt Synonym Gene Names
XAP2; AIP; XAP-2  [Similar Products]
UniProt Entry Name
AIP_HUMAN
NCBI Summary for AIP
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
UniProt Comments for AIP
AIP: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Defects in AIP are a cause of growth hormone-secreting pituitary adenoma (GHSPA); also known as familial isolated somatotropinomas (FIS) or isolated familial somatotropinoma (IFS) or familial somatotrophinoma or acromegaly due to pituitary adenoma. Defects in AIP are a cause of ACTH-secreting pituitary adenoma (ASPA); also known as pituitary Cushing disease. A pituary adenoma resulting in excessive production of adrenocorticotropic hormone. This leads to hypersecretion of cortisol by the adrenal glands and ACTH-dependent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes. Defects in AIP are a cause of prolactin-secreting pituitary adenoma (PSPA); also known as prolactinoma. Prolactin-secreting pituitary adenoma is the most common type of hormonally active pituitary adenoma.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: aryl hydrocarbon receptor binding; protein binding; signal transducer activity; transcription coactivator activity; transcription factor binding; unfolded protein binding

Biological Process: negative regulation of cyclic-nucleotide phosphodiesterase activity; protein maturation via protein folding; protein targeting to mitochondrion; signal transduction; xenobiotic metabolic process

Disease: Pituitary Adenoma, Acth-secreting; Pituitary Adenoma, Growth Hormone-secreting; Pituitary Adenoma, Prolactin-secreting
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with AIP peptide
 Products by Pathway  Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
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